myoinositol
Small moleculeexperimental
myo-Inositol trispyrophosphate (ITPP) is an inositol phosphate, a pyrophosphate, a drug candidate, and a putative performance-enhancing substance, which exerts its biological effects by increasing tissue oxygenation. — Wikipedia
Clinical trial activity
91 trials · 111 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
20
Phase 3
13
Phase 4
17
Earliest trial started Sep 1, 1998 (NCT00012558)
Timeline
Indications
Approved for
Studied for
- Anovulation · Phase 2
- Anxiety · Phase 1/Phase 2
- Anxiety Disorders · Phase 1/Phase 2
- Asthenozoospermia · Phase 2/Phase 3
- Autism Spectrum Disorder · Phase 4
- Autistic Disorder · Phase 4
- Bipolar Disorder · Phase 4
- Bronchopulmonary Dysplasia · Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Cholangiocarcinoma · Phase 1/Phase 2
- Clomiphene · Phase 4
- Colitis, Ulcerative · Phase 1/Phase 2
- Colonic Neoplasms · Phase 1/Phase 2
- Colorectal Neoplasms · Phase 1/Phase 2
- Crohn Disease · Phase 1/Phase 2
- Cryopreservation · Phase 1/Phase 2
- Depression · Phase 4
- Diabetes, Gestational · Phase 4
- Diabetes Mellitus, Type 1 · Phase 3
- Dietary Supplements · Phase 4
- Fatigue · Phase 4
- Fertilization in Vitro · Phase 3
- Glucose Intolerance · Phase 2
- Hair · Phase 2
- Humans · Phase 1/Phase 2
- Hyperandrogenism · Phase 2
- Hyperglycemia · Phase 3
- Infant, Low Birth Weight · Phase 2
- Infant, Newborn · Phase 2
- Infant, Premature · Phase 2
- Infant, Small for Gestational Age · Phase 2
- Infertility · Phase 4
- Infertility, Female · Phase 3
- Infertility, Male · Phase 4
- Inositol · Phase 4
- Insulin Resistance · Phase 4
- Learning Disabilities · Phase 4
- Liver Neoplasms · Phase 1/Phase 2
- Lung Diseases · Phase 2
- Lung Neoplasms · Phase 1
- Menopause · Phase 2/Phase 3
- Metabolic Diseases · Phase 2
- Metabolic Syndrome · Phase 4
- Mood Disorders · Phase 4
- Neural Tube Defects · Phase 1
- Obesity · Phase 4
- Oligospermia · Phase 2/Phase 3
- Ovarian Diseases · Phase 2/Phase 3
- Ovulation Induction · Phase 4
- Pancreatic Neoplasms · Phase 1/Phase 2
- Pediatric Obesity · Phase 4
- Periodontitis · Phase 2
- Polycystic Ovary Syndrome · Phase 4
- Precancerous Conditions · Phase 1
- Reproductive Medicine · Phase 3
- Retinopathy of Prematurity · Phase 3
- Spermatozoa · Phase 1/Phase 2
- Trichotillomania · Phase 2
- Zinc · Phase 4
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
Loading structure…
SMILES
O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O- Mol. weight
- 180.16 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMyo-Inositol trispyrophosphate ↗
- ChEMBLCHEMBL1222251 ↗
- WikipediaMyo-inositol trispyrophosphate ↗
- WikipediaInositol ↗
Also known as
- 1,2,3,5/4,6-cyclohexanehexol
- 1,2,3,5/4,6-cyclohexanehexol
- cis-1,2,3,5-trans-4,6-cyclohexanehexol
- cis-1,2,3,5-trans-4,6-cyclohexanehexol
- cyclohexanehexol
- cyclohexanehexol
- cyclohexanehexol
- cyclohexitol
- d-chiro-inositol
- d-chiro-inositol
- d-chito-inositol
- inosital
- inositene
- inositina
- inositol
- inositol
- inositol
- inositol
- inositol
- inositol
- inositol
- inositol
- l-myo-inositol
- l-myo-inositol
- mesoinositol
- meso-inositol
- meso-inositol
- myoinosite
- myoinositol
- myoinositol
- myoinositol
- myo-inositol
- myo-inositol
- myo-inositol
- myo-inositol
- myo-inositol trispyrophosphate
- oxy111a
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07266259 | N/A | Sep 19, 2025 | Bangladesh Medical University |
| NCT06800170 | N/A | May 1, 2025 | AGUNCO Obstetrics and Gynecology Centre, Lo.Li. Pharma, Ltd. |
| NCT06840613 | N/A | Mar 31, 2025 | University of Health Sciences Lahore |
| NCT06575868 | N/A | Jan 1, 2025 | Tufts University |
| NCT07058675 | N/A | Nov 25, 2024 | Benha University |
| NCT06715527 | N/A | Nov 1, 2024 | Lo.Li. Pharma, Ltd. |
| NCT06736015 | N/A | Oct 23, 2024 | ISTITUTO REGINA ELENA |
| NCT06405243 | Phase 3 | Jun 30, 2024 | Beni Suef University |
| NCT06405204 | Phase 3 | Jun 30, 2024 | Beni Suef University |
| NCT06158932 | N/A | Sep 8, 2023 | Citruslabs, Optify |
| NCT05900661 | Phase 2/Phase 3 (Phase 3) | Jul 30, 2023 | Beni Suef University |
| NCT05678114 | N/A | Dec 21, 2022 | Lo.Li. Pharma, Ltd. |
| NCT06170463 | Phase 1 | Aug 1, 2022 | Zagazig University |
| NCT05951309 | N/A | Sep 1, 2021 | Cyprus International University, Near East University, Turkey |
| NCT05943158 | N/A | Jun 1, 2021 | Cyprus International University, Near East University, Turkey |
| NCT04892186 | N/A | May 20, 2021 | University of Sao Paulo |
| NCT04867252 | Phase 2 | May 3, 2021 | Khyber Medical University Peshawar |
| NCT04745780 | N/A | Feb 10, 2021 | Lo.Li. Pharma, Ltd. |
| NCT04801485 | N/A | Jan 1, 2021 | Quzhou Maternal and Child Health Care Hospital, Zhejiang University |
| NCT04576546 | N/A | Nov 2, 2020 | Lo.Li. Pharma, Ltd. |
Showing 20 of 91 trials
Page 1 / 5
Organizations
Research & Development (111)
111 organizations
Page 1 / 6