perfluorooctyl bromide
Trade name: Imagent
Small moleculeapproved
Approved
Aug 13, 1993
Perflubron is a contrast medium for magnetic resonance imaging, computer tomography and sonography. It was approved for this use in the United States by the Food and Drug Administration in 1993. — Wikipedia
Clinical trial activity
1 trials · 2 clinical orgs · 1 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2017 (NCT03041740)
Timeline
1990s
- Aug 13, 1993
Alliance Pharmaceutical Corp. — Earliest FDA Approval
- Aug 13, 1993
Alliance Pharmaceutical Corp. — NDA Secondary Org
- Aug 13, 1993
Alliance Pharmaceutical Corp. — NDA Organization
2010s
- Jan 1, 2017
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Studied for
Mechanism of action
- Unspecified targetOTHER
Diagnostic
- contrast mediumRadiopaque
contrast medium radiopaque
- UnclearUnclear
Unclear unclear
Approval history
- approvedPriority reviewAug 13, 1993
Chemistry & pharmacology
Loading structure…
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F- Mol. weight
- 338.0418 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- WikipediaPerflubron ↗
- NCATSFX3WJ41CMX ↗
- ChEMBLCHEMBL1200866 ↗
- ChEMBLCHEMBL1200607 ↗
- NCATSQ1D0Q7R4D9 ↗
Also known as
- af0144
- af0150
- af0150
- af-0150
- af-0150
- afo 150
- dimyristoyl lecithin; perflexane perflubron
- imagent
- imagent
- imagent
- imagent
- imagent bp
- imagent gi
- imavist
- l 1913
- l-1913
- la11063
- la 11063
- oxygent
- perflexane
- perflexane
- perflexane
- perflexane
- perflexane
- perflubron
- perflubron
- perflubron
- perflubron
- perflubron
- perflubron
- perflubron
- perflubron
- perflubron emulsion
- perfluoroctylbromide
- perfluoroctyl bromide
- perfluorohexane
- perfluorohexane
- perfluorohexane
- perfluorohexane
- perfluorohexane
- perfluoro-n-hexane
- perfluorooctylbromide
- perfluorooctylbromide
- perfluorooctylbromide
- perfluorooctylbromide
- perfluorooctyl bromide
- perfluorooctyl bromide
- perfluorooctyliodide
- perfluorooctyl iodide
- pfob
- pfob
- pfob
- tetradecafluorohexane
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03041740 | Early Phase 1 (Phase 1) | Jun 1, 2017 | ADAGP Charitable Foundation, University of Pennsylvania |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| ADAGP Charitable Foundation | Academic/Hospital | 1 | 0 | 1 | 2017 |
| University of Pennsylvania | Academic/Hospital | 1 | 1 | 1 | 2017 |
2 organizations
Page 1 / 1
Marketing (2)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Alliance Pharmaceutical Corp. | For profit | NDA2 | Aug 13, 1993 |
| Alliance Pharmaceutical Corp. | For profit | NDA | Aug 13, 1993 |