CDEK
← All drugs Report issue

enterococcus faecium

Cell therapyexperimental

Enterococcus is a large genus of lactic acid bacteria of the phylum Bacillota. Enterococci are Gram-positive cocci that often occur in pairs (diplococci) or short chains, and are difficult to distinguish from streptococci on physical characteristics alone. Two species are common commensal organisms in the intestines of humans: E. faecalis (90–95%) and E. faecium (5–10%). Rare clusters of infections occur with other species, including E. durans, E. casseliflavus, E. gallinarum, and E. raffinosus. — Wikipedia

Clinical trial activity

30 trials · 43 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
8
Phase 3
7
Phase 4
5

Earliest trial started Feb 1, 2006 (NCT00587041)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2018

    Earliest Phase 3 Sponsor(trial)

2020s

  1. Jan 1, 2021

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • microbiotaTissue restoration

    microbiota tissue restoration

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • enterococcus
  • enterococcus faecium
  • enterococcus faecium w54

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06449508Phase 1/Phase 2 (Phase 2)Jul 1, 2024Tanta University
NCT07285317Phase 1Feb 1, 2024Government of Spain
NCT07065942N/AJul 1, 2023Beijing Huaxin Hospital, Capital Medical University, Chinese Academy of Medical Sciences, Peking University
NCT06151392Phase 4Jul 1, 2023Ain Shams University
NCT05776940Phase 3Mar 31, 2023Air Force Military Medical University, China
NCT06253988Phase 3Jan 1, 2023Al Azhar University, Assiut University, Sphinx university
NCT05663060N/ADec 13, 2022Istituto Clinico Humanitas - Rozzano (MI), Italy
NCT05688618N/ANov 16, 2022Anahuac University
NCT06422000Phase 3Jun 30, 2022Tanta University
NCT05682807Phase 3Jun 30, 2022Tanta University
NCT05220124Phase 4Jan 5, 2022Tianjin Medical University
NCT05088369Early Phase 1 (Phase 1)Nov 30, 2021Government of China, Nucleus Network Ltd, Syneos Health
NCT05629468Phase 3Oct 15, 2021Government of Pakistan, Riphah International University
NCT04871464Phase 4Sep 30, 2021Capital Medical University
NCT05086458N/AAug 17, 2021Huazhong University of Science and Technology
NCT04982380Phase 4Jul 31, 2021Chengde Medical University, Chinese Academy of Medical Sciences, Hangzhou Grand Biologic Pharmaceutical, Inc., Harbin Medical University, Inner Mongolia Medical University, Zhengzhou University
NCT05911022N/AJul 1, 2021Ain Shams University
NCT04802785Phase 2/Phase 3 (Phase 3)Jun 30, 2021lurye Clinic
NCT05178524N/AJun 1, 2021Huazhong University of Science and Technology
NCT04659408N/AMar 1, 2021Swiss Paraplegic Centre Nottwil
Showing 20 of 30 trials
Page 1 / 2

Organizations

Research & Development (43)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Huazhong University of Science and TechnologyAcademic/Hospital3322018
Tanta UniversityAcademic/Hospital3322022
Ain Shams UniversityAcademic/Hospital2222021
Capital Medical UniversityAcademic/Hospital2122021
Chinese Academy of Medical SciencesAcademic/Hospital2222021
Jiao Tong UniversityAcademic/Hospital2122016
Medical University of GrazAcademic/Hospital2212015
Air Force Military Medical University, ChinaAcademic/Hospital1112023
Al Azhar UniversityAcademic/Hospital1112023
Anahuac UniversityAcademic/Hospital1112022
Assiut UniversityAcademic/Hospital1012023
Beijing Huaxin HospitalAcademic/Hospital1012023
Central South UniversityAcademic/Hospital1112017
Chengde Medical UniversityAcademic/Hospital1012021
Eskisehir Osmangazi UniversityAcademic/Hospital1112012
Government of ChinaGovernment1012021
Government of PakistanGovernment1112021
Government of SpainGovernment1112024
Hangzhou Grand Biologic Pharmaceutical, Inc.Government1012021
Harbin Medical UniversityAcademic/Hospital1012021
43 organizations
Page 1 / 3