phosphatidylglycerol
Small moleculeexperimental
Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant and in the plasma membrane where it directly activates lipid-gated ion channels. — Wikipedia
Clinical trial activity
9 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
9
Phase 3
1
Phase 4
0
Earliest trial started Mar 1, 2000 (NCT00004500)
Timeline
Indications
Studied for
- Bronchopulmonary Dysplasia · Phase 2
- Cystic Fibrosis · Phase 2
- Meconium Aspiration Syndrome · Phase 3
- Obesity · Phase 2
- Premature Birth · Phase 2
- Respiratory Distress Syndrome · Phase 2
- Respiratory Distress Syndrome, Newborn · Phase 2
- Respiratory Insufficiency · Phase 2
- Sleep Apnea, Obstructive · Phase 2
- Sleep Apnea Syndromes · Phase 2
Mechanism of action
- Unspecified targetSurfactant
surfactant
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPhosphatidylglycerol ↗
Also known as
- phosphatidylglycerol
- phosphatidylglycerol
- phosphatidylglycerol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02636868 | Phase 2 | Dec 1, 2015 | Windtree Therapeutics |
| NCT02528318 | Phase 2 | Aug 1, 2015 | National Heart, Lung, and Blood Institute (NHLBI), Windtree Therapeutics |
| NCT01765608 | Phase 2 | Mar 1, 2010 | Eisai, University of Gothenburg |
| NCT00934362 | Phase 2 | Oct 1, 2008 | Cystic Fibrosis Foundation Therapeutics, University of North Carolina at Chapel Hill, Windtree Therapeutics |
| NCT00578734 | Phase 2 | Jun 1, 2007 | Harvard University, Pennsylvania State University, Windtree Therapeutics |
| NCT00215540 | Phase 2 | Feb 1, 2005 | University of North Carolina at Chapel Hill, Windtree Therapeutics |
| NCT00807235 | Phase 2 | Jan 1, 2005 | University of California, San Diego, Windtree Therapeutics |
| NCT00215553 | Phase 2 | May 1, 2001 | Windtree Therapeutics |
| NCT00004500 | Phase 3 | Mar 1, 2000 | Windtree Therapeutics |
Showing 9 of 9 trials
Page 1 / 1
Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Windtree Therapeutics | For profit | 8 | 7 | 2 | 2000 |
| University of North Carolina at Chapel Hill | Academic/Hospital | 2 | 1 | 1 | 2005 |
| Cystic Fibrosis Foundation Therapeutics | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Eisai | For profit | 1 | 0 | 1 | 2010 |
| Harvard University | Academic/Hospital | 1 | 0 | 1 | 2007 |
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 1 | 0 | 1 | 2015 |
| Pennsylvania State University | Academic/Hospital | 1 | 0 | 1 | 2007 |
| University of California, San Diego | Academic/Hospital | 1 | 0 | 1 | 2005 |
| University of Gothenburg | Academic/Hospital | 1 | 1 | 1 | 2010 |
9 organizations
Page 1 / 1