Status Epilepticus
A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
Subtype terms (1)
More specific conditions that are subtypes of Status Epilepticus in the MeSH hierarchy.
- Epilepsia Partialis Continua
3 drugs approved
Drugs by status
Approved for this indication (3)
Phase 4 trials (4)
Phase 3 trials (14)
Phase 2 trials (1)
Other trials (1)
Organizations
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 3 Indications (39)
- Shire
- Pfizer
- Marinus Pharmaceuticals
- Sage Therapeutics
- National Institutes of Health (NIH)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
- Bambino Gesù Hospital and Research Institute
- Harvard University
- Northwestern University
- University of Florence
- University of Lausanne
- University of Michigan
- University of Padova
- University of Bologna
- Marche Polytechnic University
- University of Virginia
- Mayo Clinic
- University of California, San Francisco
- University of Cape Town
- Medical University of South Carolina
- All India Institute of Medical Sciences
- University of Trieste
- University of Minnesota
- Badalona Hospital Germans Trias i Pujol
- Mid-Atlantic Epilepsy and Sleep Center
- University of Malawi
- Nuovo Regina Margherita Hospital
- Technion University
- Sorbonne University
- +9 more
Organization Involved with Phase 2 Indications (6)
Organization Involved with Phase 1 Indications (1)
Organization Involved with Other Experimental Indications (9)