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Hepatitis B
INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Subtype terms (1)
More specific conditions that are subtypes of Hepatitis B in the MeSH hierarchy.
- Hepatitis B, Chronic
220 drugs (60 approved, 160 experimental)
Drugs by status
Approved for this indication (12)
- adefovir dipivoxil
- besifovir
- entecavir
- DTaP, inactivated poliovirus, haemophilus influenzae b conjugate, hepatitis b vaccine
- lamivudine
- hepatitis b vaccine (recombinant)
- interferon alfa-1b
- hepatitis b immune globulin (human)
- hepatitis-a virus (inactivated) / hepatitis-b surface antigen
- interferon alpha-2b
- HBV DNA vaccine
- clevudine
Phase 4 trials (32)
- efavirenz
- vitamin d3
- calcium carbonate
- maraviroc
- urea
- cpg-oligonucleotide
- etravirine
- tacrolimus
- levocarnitine
- menitorix
- menjugate
- atorvastatin
- quinvaxem
- immune globulin (human)
- emtricitabine
- hepatitis a vaccine, inactivated
- human papillomavirus 9-valent vaccine, recombinant
- hepatitis e vaccine
- Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine
- zidovudine
- bictegravir
- fuzhenghuayu
- trianrix
- haemophilus influenzae type b conjugate vaccine
- acellular pertussis vaccine (including diptheria and tetanus toxoids)
- sargramostim
- tenofovir alafenamide
- telbivudine
- flavonoid
- s-adenosyl methionine
- +2 more
Phase 3 trials (45)
- phosphorothiolate oligodeoxyribonucleotide
- monophosphoryl lipid a
- aluminum
- berberine
- diphtheria-tetanus-whole cell pertussis-inactivated poliovirus-haemophilus influenzae b conjugate-hepatitis b vaccine
- eltrombopag
- gc1102
- hbv-mpl 208129
- haemophilus influenzae type b-neisseria meningitidis serogroups c and y-tetanus-toxoid conjugate vaccine
- aldesleukin
- ritonavir
- imiquimod
- ledipasvir
- meningococcal (groups A, C, Y, W) CRM197 conjugate vaccine
- lactose
- daclatasvir
- pneumococcal 13-valent conjugate vaccine
- ribavirin
- sofosbuvir
- tritanrix-hepb
- inactivated poliovirus type 2 vaccine
- acellular pertussis vaccine
- carvedilol
- Haemophilus influenzae Type b Conjugate and Hepatitis B (Recombinant)
- glyco-conjugate neisseria meningitidis serogroup c vaccine
- hb-as02v
- pneumococcal 7-valent conjugate vaccine
- polyribosil-ribitol-phosphate vaccine
- measles, mumps, rubella, varicella vaccine
- v232
- +15 more
Phase 2 trials (70)
- 23-valent pneumococcal polysaccharide vaccine
- gsk-287615
- gsk2231392a
- aln-hbv
- arc-520
- sorafenib
- pri-724
- prednisone
- fialuridine
- gs-4774
- dolutegravir
- gsk2036874a
- gsk3389404
- tenofovir
- rosuvastatin
- bovine colostrum
- interferon alpha-2a
- nivolumab
- jnj-56136379
- ursodeoxycholic acid
- mtl-cebpa
- pamrevlumab
- aluminum hydroxide
- pegylated-interferon
- methylene blue
- resiquimod
- ipilimumab
- lopinavir
- rep 2139
- rotavirus vaccine, live, oral, pentavalent
- +40 more
Phase 1 trials (35)
- simvastatin
- al-3778
- arc-521
- ino-1800
- hydronidone
- carbamazepine
- navitoclax
- alendronic acid
- quinidine
- rifaximin
- birinapant
- itraconazole
- vesatolimod
- advax
- cpg 7909 oligodeoxynucleotide
- cvi-hbv-002
- fp-02.2
- pres hbsag
- vax-id
- ic31
- ino-9112
- gamma-delta t cells
- tq-a3334
- crv431
- edp-514
- al-034
- ro7239958
- NCO-48 fumarate
- gst-hg141
- gst-hg131
- +5 more
Other trials (28)
- 131i-lipiodol
- didanosine
- methylprednisolone
- spirulina
- abacavir
- doxorubicin
- fluorodopa
- ethanol
- polysaccharide mgn3
- ocrelizumab
- cholesterol
- resveratrol
- human fecal microbiota
- proalgazyme
- spirulina platensis
- rhizoma atractylodis macrocephalae
- rituximab
- gardenia jasminoides ellis
- raltegravir
- artemisia
- blood plasma
- salvia
- thymalfasin
- anluohuaxian
- rubia cordifolia
- sieyesbeckiaorientalis
- paeoniae radix
- tizoxanide
Organizations
Organization Involved with Phase 4 Indications (231)
- McMaster University
- University of Wisconsin
- Burroughs Wellcome
- Zhejiang University
- Shanghai University of Traditional Chinese Medicine
- The Fifth People's Hospital of Suzhou
- Humanity & Health Research Centre
- Calmette Hospital
- Qidong Liver Cancer Institute
- Aarhus University
- French National Agency for Research on AIDS and Viral Hepatitis
- Hannover Clinical Trial Center GmbH
- China Medical University
- Singapore General Hospital
- Kangbuk Samsung Hospital
- Federal University of Goias
- Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
- University of Miami
- City University of Hong Kong
- Chung Shan Medical University
- University of California, San Diego
- Yonsei University
- University of Paris
- ChengChing Hospital
- Bukwang Pharmaceutical
- Changi General Hospital
- Gachon University
- IlDong Pharmaceutical Co Ltd
- Inha University
- Govind Ballabh Pant Institute of Postgraduate Medical Education and Research
- +201 more
Organization Involved with Phase 3 Indications (68)
- German Liver Foundation
- National Institutes of Health (NIH)
- National Institute of Allergy and Infectious Diseases (NIAID)
- Aclin Laboratories, Chile
- Sanofi-Aventis
- University of Burgundy
- University of Texas at Houston
- University of Pittsburgh
- Beijing Tiantan Bio Co., Ltd
- Biotest Pharmaceuticals
- Sheffield Hallam University
- University of Ottawa
- Banha Fever Hospital
- Wonju Christian Hospital
- Eisai
- Grifols
- Government of Indonesia
- The Egyptian Company for Blood Transfusion Services
- Bangladesh Medical University
- Alexandria University
- Dynavax Technologies Corporation
- National Heart, Lung, and Blood Institute (NHLBI)
- Schering-Plough
- Mahidol University
- Ewha Womans University
- Guangzhou Medical University
- Hopital Paul Brousse
- Southwest Oncology Group
- Mayo Clinic
- Central South University
- +38 more
Organization Involved with Phase 2 Indications (107)
- Eurofins
- Gouya Insights
- Department of Veteran Affairs
- Pharmaceutical Research Associates, Inc. (PRA)
- Biomay AG
- InterMune
- University of Texas, San Antonio
- Altimmune, Inc.
- Assembly Biosciences
- Japan Agency for Medical Research and Development
- Duke University
- Centers for Disease Control and Prevention, Division of Reproductive Health
- Vaxine Pty Ltd
- Triangle Pharmaceuticals
- University of Antwerp
- Tokyo Metropolitan Komagome Hospital
- Human Genome Sciences
- Shanghai Genomics, Inc.
- Arrowhead Pharmaceuticals
- Medical University of Vienna
- Prodia StemCell Indonesia
- University of Padova
- Enyo Pharma
- The HIV Netherlands Australia Thailand Research Collaboration
- Australian Respiratory and Sleep Medicine Institute
- Brii Biosciences
- Free University of Brussels
- Oclassen
- Alios BioPharma
- University of Rochester
- +77 more
Organization Involved with Phase 1 Indications (33)
- Transgene
- Hengrui Therapeutics, Inc.
- Novira Therapeutics, Inc.
- Johnson and Johnson
- Barinthus Biopharmaceuticals
- Cathay General Hospital
- Inovio Pharmaceuticals
- GNI Group
- PowderMed
- Immutep S.A.
- Antios Therapeutics, Inc
- Jinan University
- Novosanis NV
- Hepion Pharmaceuticals
- CPR Pharma Services Pty Ltd, Australia
- Sclnow Biotechnology Co., Ltd.
- Dicerna Pharmaceuticals, Inc.
- Maharaj Nakorn Chiang Mai Hospital
- Padjadjaran University
- Genexine, Inc.
- SGS Life Sciences
- PharmaEssentia Corp.
- Ligand Pharmaceuticals
- IDT Australia Ltd.
- University of Oklahoma
- Nucorion Pharmaceuticals, Inc.
- Enanta Pharmaceuticals
- Aligos Therapeutics
- Medpace, Inc.
- Siriraj Hospital
- +3 more
Organization Involved with Other Experimental Indications (44)
- Technion University
- Triệu, Nguyễn Thị, M.D.
- Institute of Liver and Biliary Sciences, India
- Mercy Hospital for Women, Australia
- Changhai Hospital
- Ben Gurion University
- Karolinska Institute
- University of Melbourne
- Murdoch University
- Government of Hong Kong
- Hangzhou Xixi hospital
- Vietnamese Military
- New Jeddah Clinic Hospital
- Maimonides Medical Center
- University of Yaounde
- Charles Drew University
- Tran Minh Duc, Dr.
- Corporacion Parc Tauli
- Universidad Carlos III Madrid
- Bar Ilan University
- Shenzhen University
- SciGen, Israel
- Zagazig University
- Hunan University of Traditional Chinese Medicine
- Northwestern University
- University of Louisville
- Narayana Hrudayalaya Limited
- Hepa C
- ZIVO Bioscience, Inc.
- Institut Hospital del Mar d'Investigacions Mèdiques
- +14 more