hepatitis e vaccine
Vaccineexperimental
Clinical trial activity
16 trials · 18 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
6
Phase 3
2
Phase 4
9
Earliest trial started Feb 1, 2000 (NCT00287469)
Timeline
Indications
Approved for
Studied for
- Cervical Intraepithelial Neoplasia · Phase 3
- Condylomata Acuminata · Phase 2
- Hepatitis · Phase 2
- Hepatitis B · Phase 4
- Hepatitis C, Chronic · Phase 4
- Hepatitis E · Phase 4
- Hepatitis E virus · Phase 4
- Human papillomavirus 16 · Phase 4
- Papillomavirus Infections · Phase 4
- Persistent Infection · Phase 3
- Uterine Cervical Neoplasms · Phase 3
- Vaginal Neoplasms · Phase 3
- Vulvar Neoplasms · Phase 3
Mechanism of action
- hepatitis e virusImmunity, active
hepatitis e virus immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- hecolin
- hecolin
- hepatitis e vaccine
- hev 239
- recombinant (e. coli) hepatitis e vaccine
- recombinant hepatitis e vaccine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06306196 | Phase 2 | Apr 30, 2024 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Bill and Melinda Gates Foundation, International Vaccine Institute |
| NCT05808166 | Phase 2 | May 31, 2023 | Bill and Melinda Gates Foundation, International Vaccine Institute, Open Philanthropy Project, Thrasher Research Fund |
| NCT06564116 | Phase 4 | Mar 22, 2023 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT05415345 | Phase 4 | Oct 25, 2021 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT03365921 | Phase 4 | Dec 31, 2017 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT03168412 | Phase 4 | May 26, 2017 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT02964910 | Phase 4 | Sep 1, 2016 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT02759991 | Phase 4 | Jun 1, 2016 | Government of Norway, International Center for Diarrheal Disease Research, Sykehuset Innlandet HF |
| NCT02710851 | Phase 2 | Mar 1, 2016 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China, University of Michigan, Xiamen University |
| NCT02584543 | Phase 4 | Oct 1, 2015 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China |
| NCT02603055 | Phase 1 | Jul 1, 2015 | Changchun Institute of Biological Products Co., Ltd., Government of China |
| NCT02417597 | Phase 4 | Apr 1, 2015 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China, Xiamen University |
| NCT02189603 | Phase 4 | Jun 1, 2014 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., University of Michigan, Xiamen Center for Disease Control and Prevention, Xiamen University |
| NCT01735006 | Phase 3 | Nov 1, 2012 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Chinese Academy of Medical Sciences, Government of China, Xiamen University |
| NCT01014845 | Phase 3 | Aug 1, 2007 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Government of China, Xiamen University |
| NCT00287469 | Phase 2 | Feb 1, 2000 | GlaxoSmithKline, Government of Thailand, National Institute of Allergy and Infectious Diseases (NIAID), United States Army |
Showing 16 of 16 trials
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Organizations
Research & Development (18)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | For profit | 12 | 7 | 3 | 2007 |
| Government of China | Government | 11 | 1 | 4 | 2007 |
| Xiamen University | Academic/Hospital | 5 | 2 | 3 | 2007 |
| Bill and Melinda Gates Foundation | Academic/Hospital | 2 | 0 | 1 | 2023 |
| International Vaccine Institute | Academic/Hospital | 2 | 2 | 1 | 2023 |
| University of Michigan | Academic/Hospital | 2 | 2 | 2 | 2014 |
| Changchun Institute of Biological Products Co., Ltd. | For profit | 1 | 0 | 1 | 2015 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2012 |
| GlaxoSmithKline | For profit | 1 | 0 | 1 | 2000 |
| Government of Norway | Government | 1 | 1 | 1 | 2016 |
| Government of Thailand | Government | 1 | 0 | 1 | 2000 |
| International Center for Diarrheal Disease Research | Academic/Hospital | 1 | 0 | 1 | 2016 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 0 | 1 | 2000 |
| Open Philanthropy Project | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Sykehuset Innlandet HF | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Thrasher Research Fund | Academic/Hospital | 1 | 0 | 1 | 2023 |
| United States Army | Government | 1 | 1 | 1 | 2000 |
| Xiamen Center for Disease Control and Prevention | Government | 1 | 0 | 1 | 2014 |
18 organizations
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