CDEK by Data4ThePeople
Sign in Sign up
← All drugs Report issue

pamrevlumab

mAbexperimental

Pamrevlumab is a humanized monoclonal antibody designed for the treatment of idiopathic pulmonary fibrosis and pancreatic cancer. It binds to the connective tissue growth factor (CTGF) protein. — Wikipedia

Clinical trial activity

19 trials · 46 clinical orgs · 0 marketing orgs

Phase 1
6
Phase 2
12
Phase 3
6
Phase 4
0

Earliest trial started Dec 18, 2003 (NCT00074698)

Timeline

2000s

  1. Jan 1, 2003

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Multi-specific
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • fg3019
  • fg 3019
  • fg-3019
  • fg-3019
  • fg-3019
  • fg-3019
  • pamrevlumab

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04632940Phase 3Dec 31, 2020FibroGen
NCT04419558Phase 3Aug 31, 2020FibroGen
NCT04432298Phase 2Jun 30, 2020FibroGen
NCT04371666Phase 3May 30, 2020FibroGen
NCT05262309Phase 2/Phase 3 (Phase 3)May 12, 2020Universita' Cattolica del Sacro Cuore
NCT03955146Phase 3Jun 30, 2019FibroGen
NCT03941093Phase 3May 10, 2019FibroGen
NCT02851381N/AAug 1, 2016University of California, Los Angeles
NCT02606136Phase 2Nov 1, 2015FibroGen
NCT02210559Phase 1/Phase 2 (Phase 2)Jul 1, 2014FibroGen, Virginia Mason Medical Center
NCT01890265Phase 2Jun 1, 2013Avanza Research, Bharti Hospital, Columbia University, Dartmouth University, Daw Park Repatriation, Australia, Dunedin Public Hospital, New Zealand, Emory University, FibroGen, Fortis Hospitals, India, Henry Ford Health System, Into Research, South Africa, Legacy Health System, Life Mount Edgecombe Hospital, South Africa, Midland Healthcare & Research Center, India, Northwestern University, Pulmonix LLC, USA, Rajiv Gandhi University of Health Sciences, Sri Bala Medical Centre and Hospital, India, Stellenbosch University, Tauranga Hospital, New Zealand, The University of Texas, Dallas, Tokuda Hospital, Tufts University, University of Alabama, Birmingham, University of California, Davis, University of California, Los Angeles, University of Cincinnati, University of Colorado, Denver, University of Kansas, University of Louisville, University of Maryland, University of Otago, University of Pittsburgh, University of Sydney, University of Utah, Vanderbilt University, Vermont Lung Center, Via Christi Regional Medical Center, Waikato Hospital, Yale University
NCT01262001Phase 2Mar 1, 2011FibroGen
NCT01217632Phase 2Aug 1, 2010FibroGen
NCT00913393Phase 2Feb 1, 2009FibroGen
NCT01181245Phase 1Dec 1, 2008Case Western Reserve University, Dartmouth University, FibroGen, Oregon Health and Science University, Stanford University, University of Pennsylvania, University of Pittsburgh, Virginia Mason Medical Center
NCT00782561Phase 1Apr 1, 2008FibroGen
NCT00754143Phase 1Mar 1, 2008FibroGen
NCT00102297Phase 1Jan 1, 2005FibroGen
NCT00074698Phase 1Dec 18, 2003FibroGen
Showing 19 of 19 trials
Page 1 / 1

Organizations

Research & Development (46)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
FibroGenFor profit171732003
Dartmouth UniversityAcademic/Hospital2022008
University of California, Los AngelesAcademic/Hospital2122013
University of PittsburghAcademic/Hospital2022008
Virginia Mason Medical CenterAcademic/Hospital2022008
Avanza ResearchFor profit1012013
Bharti HospitalAcademic/Hospital1012013
Case Western Reserve UniversityAcademic/Hospital1012008
Columbia UniversityAcademic/Hospital1012013
Daw Park Repatriation, AustraliaAcademic/Hospital1012013
Dunedin Public Hospital, New ZealandAcademic/Hospital1012013
Emory UniversityAcademic/Hospital1012013
Fortis Hospitals, IndiaAcademic/Hospital1012013
Henry Ford Health SystemAcademic/Hospital1012013
Into Research, South AfricaAcademic/Hospital1012013
Legacy Health SystemAcademic/Hospital1012013
Life Mount Edgecombe Hospital, South AfricaAcademic/Hospital1012013
Midland Healthcare & Research Center, IndiaAcademic/Hospital1012013
Northwestern UniversityAcademic/Hospital1012013
Oregon Health and Science UniversityAcademic/Hospital1012008
46 organizations
Page 1 / 3