pri-724
Small moleculeexperimental
Clinical trial activity
6 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Feb 1, 2011 (NCT01302405)
Timeline
Indications
Studied for
- Colorectal Neoplasms · Phase 2
- Hepatitis B · Phase 1/Phase 2
- Hepatitis C · Phase 1/Phase 2
- Hepatitis C, Chronic · Phase 1
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 1/Phase 2
- Leukemia, Myeloid, Acute · Phase 1/Phase 2
- Liver Cirrhosis · Phase 1/Phase 2
- Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1
Mechanism of action
- CREB-binding proteinINHIBITOR
CREBBP inhibitor
- CBP/beta cateninINHIBITOR
CBP/beta catenin inhibitor
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297813 ↗
Also known as
- pri-724
- pri-724
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03620474 | Phase 1/Phase 2 (Phase 2) | Jul 24, 2018 | Japan Agency for Medical Research and Development, Kyushu University, National Center for Global Health and Medicine, Prism Research, Tokyo Metropolitan Komagome Hospital |
| NCT02413853 | Phase 2 | Nov 1, 2015 | National Cancer Institute (NCI), Prism Research, University of Southern California |
| NCT02195440 | Phase 1 | Aug 1, 2014 | Prism Research, Tokyo Metropolitan Komagome Hospital |
| NCT01764477 | Phase 1 | Apr 1, 2013 | inVentiv, Mayo Clinic, Prism Research |
| NCT01606579 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2012 | inVentiv, Prism Research, University of Texas at Houston |
| NCT01302405 | Phase 1 | Feb 1, 2011 | inVentiv, Prism Research, University of Southern California |
Showing 6 of 6 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Prism Research | For profit | 6 | 3 | 2 | 2011 |
| inVentiv | For profit | 3 | 0 | 2 | 2011 |
| Tokyo Metropolitan Komagome Hospital | Academic/Hospital | 2 | 2 | 2 | 2014 |
| University of Southern California | Academic/Hospital | 2 | 1 | 2 | 2011 |
| Japan Agency for Medical Research and Development | Government | 1 | 0 | 1 | 2018 |
| Kyushu University | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Mayo Clinic | Academic/Hospital | 1 | 0 | 1 | 2013 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2015 |
| National Center for Global Health and Medicine | Government | 1 | 0 | 1 | 2018 |
| University of Texas at Houston | Academic/Hospital | 1 | 0 | 1 | 2012 |
10 organizations
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