vesatolimod
Small moleculeexperimental
Clinical trial activity
11 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
7
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Mar 1, 2012 (NCT01591668)
Timeline
Indications
Mechanism of action
- Toll-like receptor 7ACTIVATOR
Toll-like receptor 7 activator
- Toll-like receptor 7AGONIST
TLR7 agonist
Chemistry & pharmacology
Loading structure…
SMILES
CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2- Mol. weight
- 410.52 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2424780 ↗
Also known as
- gs-9620
- gs-9620
- vesatolimod
- vesatolimod
- vesatolimod
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06071767 | Phase 1/Phase 2 (Phase 2) | Jan 2, 2024 | Gilead Sciences, National Institute of Allergy and Infectious Diseases (NIAID), University of Oxford, University of Pittsburgh |
| NCT05458102 | Phase 1 | Aug 19, 2022 | Gilead Sciences |
| NCT05281510 | Phase 2 | Jun 9, 2022 | Gilead Sciences |
| NCT04364035 | Phase 2 | Feb 20, 2020 | Aelix Therapeutics, Autonomous University of Madrid, Gilead Sciences |
| NCT03060447 | Phase 1 | May 9, 2017 | Gilead Sciences |
| NCT02579382 | Phase 2 | Nov 10, 2015 | Gilead Sciences |
| NCT02858401 | Phase 1 | Jan 29, 2015 | Gilead Sciences |
| NCT02166047 | Phase 2 | Jun 1, 2014 | Gilead Sciences |
| NCT01590641 | Phase 1 | Apr 1, 2012 | Gilead Sciences |
| NCT01590654 | Phase 1 | Apr 1, 2012 | Gilead Sciences |
| NCT01591668 | Phase 1 | Mar 1, 2012 | Gilead Sciences |
Showing 11 of 11 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Gilead Sciences | For profit | 11 | 9 | 2 | 2012 |
| Aelix Therapeutics | For profit | 1 | 1 | 1 | 2020 |
| Autonomous University of Madrid | Academic/Hospital | 1 | 0 | 1 | 2020 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 1 | 1 | 2024 |
| University of Oxford | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Pittsburgh | Academic/Hospital | 1 | 0 | 1 | 2024 |
6 organizations
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