← All organizations
Highest phase reached
Phase 4
First clinical trial
Feb 1, 2000First marketed drug
May 7, 2001First NDA
May 7, 2001Last known activity
Jan 1, 2021
Acquired by Takeda on May 9, 2008
Timeline
1990s
- Jan 1, 1993
Millennium Pharmaceuticals— Founded
- Oct 1, 1999
Leukosite— Acquired
2000s
- Jul 1, 2000
Cambridge Discovery Chemistry— Acquired
- May 7, 2001
alemtuzumab— NDA Organization
- Dec 7, 2001
COR Therapeutics— Acquired
- May 9, 2008
Takeda— Acquired By
2010s
- Nov 20, 2015
ixazomib— NDA Secondary Org
Drugs by trial phase (157 distinct, 401 trials)
Phase 4 (9 own, 0 via acquisition)
Phase 3 (34 own, 0 via acquisition)
Phase 2 (66 own, 1 via acquisition)
Phase 1 (47 own, 0 via acquisition)
Indications
Approved for
Studied for
- Acute Disease
- Adenocarcinoma
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenocarcinoma, Mucinous
- Amyloidosis
- Apnea
- Astrocytoma
- Atherosclerosis
- Basal Cell Carcinoma
- Brain Neoplasms
- Breast Neoplasms
- Burkitt Lymphoma
- Carcinoma
- Carcinoma, Adenoid Cystic
- Carcinoma, Hepatocellular
- Carcinoma, Merkel Cell
- Carcinoma, Neuroendocrine
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Ovarian Epithelial
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Central Nervous System Neoplasms
- Colitis
- Colitis, Ulcerative
- Colonic Neoplasms
- Colorectal Neoplasms
- Complex Regional Pain Syndromes
- Critical Illness
- Crohn Disease
- Cystadenocarcinoma
- Depression
- Depressive Disorder
- Depressive Disorder, Treatment-Resistant
- Diabetes Mellitus
- Digestive System Neoplasms
- Disease
- Disease Progression
- Disorders of Excessive Somnolence
- Endometrial Neoplasms
- Endometriosis
- Enteropathy-Associated T-Cell Lymphoma
- Ependymoma
- Epstein-Barr Virus Infections
- Esophageal Neoplasms
- Fallopian Tube Neoplasms
- Fistula
- Frailty
- Gastrointestinal Neoplasms
- Gastroparesis
- Genital Neoplasms, Female
- Genital Neoplasms, Male
- Glioblastoma
- Glioma
- Gliosarcoma
- Graft vs Host Disease
- Head and Neck Neoplasms
- Hodgkin Disease
- Idiopathic Hypersomnia
- Immunoblastic Lymphadenopathy
- Immunoglobulin Light-chain Amyloidosis
- Inflammatory Bowel Diseases
- Leukemia
- Leukemia, Large Granular Lymphocytic
- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukemia, Lymphoid
- Leukemia-Lymphoma, Adult T-Cell
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Leukemia, Myelomonocytic, Chronic
- Leukemia, Myelomonocytic, Juvenile
- Leukemia, Plasma Cell
- Leukemia, Prolymphocytic
- Leukemia, Prolymphocytic, T-Cell
- Leukemia, T-Cell
- Lip Neoplasms
- Liver Diseases
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Lymphoma
- Lymphoma, B-Cell
- Lymphoma, B-Cell, Marginal Zone
- Lymphoma, Extranodal NK-T-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Large-Cell, Anaplastic
- Lymphoma, Large-Cell, Immunoblastic
- Lymphoma, Mantle-Cell
- Lymphoma, Non-Hodgkin
- Lymphoma, Primary Cutaneous Anaplastic Large Cell
- Lymphoma, T-Cell
- Lymphoma, T-Cell, Cutaneous
- Lymphoma, T-Cell, Peripheral
- Lymphoproliferative Disorders
- Melanoma
- Mesothelioma
- Metaplasia
- Monosomy
- Multiple Myeloma
Marketed drugs (3)
Subsidiaries (3 direct, 3 total across the full acquisition tree)
Recent trials (50)
- NCT04484363Lead sponsorN/A—
- NCT04535557Lead sponsorN/A—
- NCT04535557Study directorN/A—
- NCT04712942CollaboratorPhase 2Jan 1, 2021
- NCT04454918Lead sponsorPhase 1Jul 30, 2020
- NCT04454918Study directorPhase 1Jul 30, 2020
- NCT04420884Study directorPhase 1Jun 29, 2020
- NCT04420884Lead sponsorPhase 1Jun 29, 2020
- NCT04278924Lead sponsorPhase 2Apr 1, 2020
- NCT04278924Study directorPhase 2Apr 1, 2020
- NCT04091438Lead sponsorPhase 1Feb 12, 2020
- NCT04118088Lead sponsorPhase 4Jan 1, 2020
- NCT04157517Lead sponsorPhase 1Dec 13, 2019
- NCT04157517Study directorPhase 1Dec 13, 2019
- NCT04075825Study directorPhase 3Oct 30, 2019
Details
- Founded
- Cambridge, MA, US Jan 1, 1993
- First NDA
- May 7, 2001
- Last known activity
- Jan 1, 2021
Designations held
- Orphan drug
- Fast track
- Priority review
- Accelerated approval
Notes
Acquired by Takeda