mln8054
Small moleculeexperimental
Clinical trial activity
2 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2005 (NCT00249301)
Timeline
2000s
- Jan 1, 2005
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
AURKA inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1- Mol. weight
- 476.87 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL259084 ↗
Also known as
- mln8054
- mln8054
- mln8054
- mln-8054
- mln-8054
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00652158 | Phase 1 | Apr 1, 2006 | Millennium Pharmaceuticals |
| NCT00249301 | Phase 1 | Oct 1, 2005 | Millennium Pharmaceuticals |
Showing 2 of 2 trials
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Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Millennium Pharmaceuticals | For profit | 2 | 2 | 1 | 2005 |
1 organizations
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