← Mechanisms of action

Epidermal growth factor receptor

PROTEIN FAMILYHomo sapiens

Linked proteins

Drugs acting on this target (40)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
epidermal growth factorAgonistexperimentalRecombinant proteinEpidermal growth factor receptor agonist
amivantamab-vmjw (Rybrevant)AntagonistapprovedmAbEpidermal growth factor receptor antagonist
icotinib (Conmana)AntagonistexperimentalSmall moleculeEpidermal growth factor receptor antagonist
mobocertinib (EXKIVITY)AntagonistapprovedSmall moleculeEpidermal growth factor receptor antagonist
ty-9591AntagonistexperimentalSmall moleculeEpidermal growth factor receptor antagonist
cart-egfr-il13ra2Binding agentexperimentalCell therapyEpidermal growth factor receptor binding agent
Losatuxizumab vedotinBinding agentexperimentalmAbEpidermal growth factor receptor binding agent
egf vaccineImmunity, activeexperimentalVaccineEpidermal growth factor receptor immunity, active
pep-3 vaccineImmunity, activeexperimentalVaccineEpidermal growth factor receptor immunity, active
abivertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
ac0010maInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
almonertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
asp-1929InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
aumolertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
BefotertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
bibw 2948 bsInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
bpi-361175InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
dacomitinib (vizimpro)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
egfrviii peptideInhibitorexperimentalPeptideEpidermal growth factor receptor inhibitor
erlotinib (tarceva)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
furmonertinib (Ives)InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
hemay020InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
hki-357InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
LarotinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
lazertinib (Lazcluze)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
limertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
naquotinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
nazartinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
neratinib maleate (nerlynx)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
nituzumabInhibitorexperimentalmAbEpidermal growth factor receptor inhibitor
OritinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
osimertinib (tagrisso)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
pf-06459988InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
poziotinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
RezivertinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
sklb1028InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
sunvozertinib (Zegfrovy)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
tarloxotinibInhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor
vandetanib (caprelsa)InhibitorapprovedSmall moleculeEpidermal growth factor receptor inhibitor
zn-e4InhibitorexperimentalSmall moleculeEpidermal growth factor receptor inhibitor