← Mechanisms of action
ERBB4
SINGLE PROTEINHomo sapiens
Preferred name: Receptor protein-tyrosine kinase erbB-4 ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| afatinib (gilotrif) | Inhibitor | approved | Small molecule | ERBB4 inhibitor |
| bms-599626 | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| bms-690514 | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| canertinib | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| dacomitinib (vizimpro) | Inhibitor | approved | Small molecule | ERBB4 inhibitor |
| fcn-411 | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| jnj-26483327 | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| neratinib maleate (nerlynx) | Inhibitor | approved | Small molecule | Receptor protein-tyrosine kinase erbB-4 inhibitor |
| pirotinib | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| pyrrolitinib | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| tarloxotinib | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |
| tas2940 | Inhibitor | experimental | Small molecule | ERBB4 inhibitor |