CDEK by Data4ThePeople
Sign in Sign up
← All drugs Report issue

sunvozertinib

Trade name: Zegfrovy

Small moleculeapproved

Approved

Jul 2, 2025

Clinical trial activity

22 trials · 16 clinical orgs · 1 marketing orgs

Phase 1
9
Phase 2
16
Phase 3
2
Phase 4
0

Earliest trial started Jun 30, 2019 (NCT03974022)

Timeline

2010s

  1. Jan 1, 2019

    Dizal (Jiangsu) Pharmaceutical Co., Ltd. — Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2021

    Dizal (Jiangsu) Pharmaceutical Co., Ltd. — Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2023

    Dizal (Jiangsu) Pharmaceutical Co., Ltd. — Earliest Phase 3 Sponsor(trial)

  3. Jul 2, 2025

    Earliest FDA Approval

  4. Jul 2, 2025

    Dizal (Jiangsu) Pharmaceutical Co., Ltd. — Marketing Organization

Indications

Approved for

Studied for

Mechanism of action

Approval history

  • approvedPriority reviewJul 2, 2025

Chemistry & pharmacology

Loading structure…

SMILES

C=CC(=O)Nc1cc(Nc2nccc(Nc3cc(Cl)c(F)cc3C(C)(C)O)n2)c(OC)cc1N1CC[C@@H](N(C)C)C1
Mol. weight
584.1 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07182682Phase 3Oct 31, 2025Dizal (Jiangsu) Pharmaceutical Co., Ltd., Huazhong University of Science and Technology, Tianjin Medical University
NCT07079475Phase 1/Phase 2 (Phase 2)Aug 31, 2025Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT06864624Phase 2Feb 18, 2025Dizal (Jiangsu) Pharmaceutical Co., Ltd., People's Liberation Army of China
NCT07117890Phase 2Feb 7, 2025Fudan University
NCT06563999Phase 2Dec 1, 2024Sun Yat-Sen University
NCT07274761Phase 2Oct 17, 2024Huazhong University of Science and Technology
NCT06355609Phase 2Jul 1, 2024Central South University
NCT06348927Phase 2Jul 1, 2024Central South University
NCT06195189Phase 1/Phase 2 (Phase 2)Feb 29, 2024Sichuan University
NCT06182761Phase 2Jan 31, 2024Fudan University
NCT06084104Phase 1Oct 17, 2023Dizal (Jiangsu) Pharmaceutical Co., Ltd., Orlando Clinical Research Center, Texas Liver Institute
NCT05926180Phase 1Jul 31, 2023Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT06295432Phase 2Jun 1, 2023Dizal (Jiangsu) Pharmaceutical Co., Ltd., Shantou University
NCT06276283Phase 2Feb 15, 2023Dizal (Jiangsu) Pharmaceutical Co., Ltd., Jiao Tong University
NCT05668988Phase 3Jan 31, 2023Dizal (Jiangsu) Pharmaceutical Co., Ltd., Huazhong University of Science and Technology
NCT05418582Phase 1Jan 25, 2022Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT05559645N/ANov 18, 2021Chinese Academy of Medical Sciences, Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT05159895Phase 1Sep 24, 2021Covance, Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT05712902Phase 2Jul 19, 2021Chinese Academy of Medical Sciences, Dizal (Jiangsu) Pharmaceutical Co., Ltd.
NCT04909242Phase 1May 6, 2021Dizal (Jiangsu) Pharmaceutical Co., Ltd., Pharmaceutical Research Associates, Inc. (PRA)
Showing 20 of 22 trials
Page 1 / 2

Organizations

Research & Development (16)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Dizal (Jiangsu) Pharmaceutical Co., Ltd.For profit151342019
Huazhong University of Science and TechnologyAcademic/Hospital3122023
Central South UniversityAcademic/Hospital2212024
Chinese Academy of Medical SciencesAcademic/Hospital2122021
Fudan UniversityAcademic/Hospital2212024
CovanceFor profit1012021
Harvard UniversityAcademic/Hospital1012019
Jiao Tong UniversityAcademic/Hospital1012023
Orlando Clinical Research CenterFor profit1012023
People's Liberation Army of ChinaGovernment1112025
Pharmaceutical Research Associates, Inc. (PRA)For profit1012021
Shantou UniversityAcademic/Hospital1012023
Sichuan UniversityAcademic/Hospital1112024
Sun Yat-Sen UniversityAcademic/Hospital1112024
Texas Liver InstituteAcademic/Hospital1012023
Tianjin Medical UniversityAcademic/Hospital1012025
16 organizations
Page 1 / 1

Marketing (1)

OrganizationOrg typeRelationshipDate
Dizal (Jiangsu) Pharmaceutical Co., Ltd.For profitMKTGJul 2, 2025