CDEK
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furmonertinib

Trade name: Ives

Small moleculeexperimental

Clinical trial activity

56 trials · 40 clinical orgs · 0 marketing orgs

Phase 1
9
Phase 2
50
Phase 3
7
Phase 4
1

Earliest trial started Aug 10, 2020 (NCT04858958)

Timeline

2020s

  1. Jan 1, 2020

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2021

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2021

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OCC(F)(F)F)nc1N(C)CCN(C)C
Mol. weight
568.6 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07298148Phase 2Jan 1, 2026Peking University
NCT07185997Phase 3Dec 31, 2025ArriVent BioPharma
NCT06668103Phase 2Dec 30, 2025Abbisko Therapeutics Co, Ltd
NCT07304739Phase 2Dec 22, 2025Tianjin Medical University
NCT07229729Phase 2Nov 30, 2025Hengrui Therapeutics, Inc.
NCT07193160Phase 2Nov 1, 2025Fudan University
NCT07182708Phase 2Oct 1, 2025Peking University
NCT07169994Phase 1/Phase 2 (Phase 2)Sep 2, 2025Suzhou Medilink Therapeutics Ltd.
NCT06962865Phase 2Jun 30, 2025Central South University, RemeGen
NCT07010419Phase 3May 28, 2025Allist Pharmaceuticals, Inc., ArriVent BioPharma, Peking University, Sun Yat-Sen University
NCT07229599Phase 1/Phase 2 (Phase 2)May 9, 2025Minghui Pharmaceutical Pty Ltd
NCT07092202Phase 4Apr 15, 2025Huazhong University of Science and Technology
NCT07087223Phase 1/Phase 2 (Phase 2)Apr 8, 2025Peking University
NCT06945705Phase 2Apr 2, 2025Henan Medical University
NCT06890182Phase 2Mar 31, 2025Tianjin Medical University
NCT06868732Phase 1Mar 12, 2025Alphamab Co., Ltd., Sun Yat-Sen University
NCT06956001Phase 3Nov 19, 2024Allist Pharmaceuticals, Inc.
NCT06812871Phase 2Nov 1, 2024Sun Yat-Sen University
NCT06652048Phase 2Oct 31, 2024Fudan University
NCT06643000N/AOct 31, 2024Henan Medical University
Showing 20 of 56 trials
Page 1 / 3

Organizations

Research & Development (40)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Allist Pharmaceuticals, Inc.For profit13732020
Sun Yat-Sen UniversityAcademic/Hospital7532021
Chinese Academy of Medical SciencesAcademic/Hospital6522022
Huazhong University of Science and TechnologyAcademic/Hospital5422021
Jiao Tong UniversityAcademic/Hospital5222020
Peking UniversityAcademic/Hospital5422021
ArriVent BioPharmaFor profit4322022
Fudan UniversityAcademic/Hospital4412021
Central South UniversityAcademic/Hospital3212022
People's Liberation Army of ChinaGovernment3112021
Tianjin Medical UniversityAcademic/Hospital3312021
Henan Medical UniversityAcademic/Hospital2222024
Zhejiang UniversityAcademic/Hospital2112021
Abbisko Therapeutics Co, LtdFor profit1112025
Alphamab Co., Ltd.For profit1112025
Beijing CSCO-Allist Cancer Research FoundationAcademic/Hospital1012021
Bengbu Medical CollegeAcademic/Hospital1012024
Changhai HospitalAcademic/Hospital1112024
Chongqing Medical UniversityAcademic/Hospital1112022
Fujian Medical UniversityAcademic/Hospital1012021
40 organizations
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