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Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
Drugs by status
Approved for this indication (1)
Phase 3 trials (12)
Phase 2 trials (38)
- azacitidine
- tioguanine
- mercaptopurine
- urea
- busulfan
- calaspargase pegol
- diphenhydramine
- prednisone
- naltrexone
- hydrocortisone
- hyaluronidase (human recombinant)
- vincristine
- pegaspargase
- acetaminophen
- ruxolitinib
- Isatuximab
- stem cells
- dasatinib
- Anti-thymocyte Globulin (Rabbit)
- bortezomib
- vorinostat
- anti-cd7 car-pnk cells
- cd45-depleted allogenic peripheral blood stem cell
- methotrexate
- fludarabine
- romidepsin
- daratumumab
- prednisolone
- mitoxantrone
- ranitidine
- +8 more
Phase 1 trials (16)
Other trials (1)
Organizations
Organization Involved with Phase 3 Indications (9)
Organization Involved with Phase 2 Indications (68)
- Spectrum Pharmaceuticals
- BioCryst
- Eli Lilly
- Sanofi
- Novartis
- Mundipharma
- PersonGen BioTherapeutics (Suzhou) Co., Ltd.
- National Institutes of Health (NIH)
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
- Cornell University
- ECOG-ACRIN Cancer Research Group
- Faculdade de Medicina do ABC
- Emory University
- Federal University of Rio Grande do Sul
- University of Washington
- Hospital Nossa Senhora da Conceicao
- Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti
- Medical College of Wisconsin
- New York Medical College
- Shenzhen Geno-Immune Medical Institute
- Southwest Oncology Group
- Sichuan University
- Tufts University
- University of Florence
- University of Florida
- University of Palermo
- University of Regensburg
- University of Rochester
- University of Southern California
- University of Toronto
- +38 more
Organization Involved with Phase 1 Indications (13)
Organization Involved with Other Experimental Indications (3)