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haploidentical mononuclear cells

Cell therapyexperimental

Clinical trial activity

20 trials · 29 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
14
Phase 3
3
Phase 4
1

Earliest trial started Aug 1, 2005 (NCT00790413)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2012

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2014

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Bone marrowTissue restoration

    bone marrow - tissue restoration

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Also known as

  • dli
  • haploidentical mononuclear cells
  • haploidentical stem cell

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06517641Phase 2Sep 1, 2024Medical College of Wisconsin, National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI), Sanofi
NCT06398808Phase 2Apr 8, 2024Zydus Discovery DMCC
NCT06381817Phase 3Apr 1, 2024Fujian Medical University, Huazhong University of Science and Technology, Jiao Tong University, Soochow University, Southern Medical University, Zhejiang University
NCT04414046Phase 2Jun 30, 2020Johns Hopkins University
NCT04356469Phase 2Jun 30, 2020Johns Hopkins University
NCT04187105Phase 2Nov 8, 2019University of Illinois at Chicago
NCT03655145Phase 3Aug 31, 2018Assistance Publique - Hôpitaux de Paris
NCT03608059Phase 4Jul 28, 2018Jiao Tong University
NCT03955601Phase 2Jul 12, 2018Government of Pakistan
NCT02918292Phase 2Sep 1, 2017Blood and Marrow Transplant Clinical Trials Network, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI), National Marrow Donor Program
NCT03381118Phase 2Jun 30, 2017Pavlov First Saint Petersburg State Medical University
NCT02566395Phase 3Dec 1, 2014Cohen Children's Medical Center of New York, New York Blood Center, Northwell Health
NCT02282904Early Phase 1 (Phase 1)Oct 22, 2014National Institute of Allergy and Infectious Diseases (NIAID)
NCT02145039N/AOct 1, 2014University of Minnesota
NCT02013375Phase 2Feb 5, 2014University of Illinois at Chicago
NCT03393611Phase 1Nov 30, 2012Cornell University
NCT01690507Phase 1/Phase 2 (Phase 2)Nov 1, 2012Government of China, People's Liberation Army of China
NCT01749293Phase 2Aug 1, 2012University of Illinois at Chicago
NCT00458250Phase 1Sep 1, 2006Isfahan University
NCT00790413Early Phase 1 (Phase 1)Aug 1, 2005Lund University
Showing 20 of 20 trials
Page 1 / 1

Organizations

Research & Development (29)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of Illinois at ChicagoAcademic/Hospital3312012
Jiao Tong UniversityAcademic/Hospital2122018
Johns Hopkins UniversityAcademic/Hospital2212020
Medical College of WisconsinAcademic/Hospital2212017
National Cancer Institute (NCI)Government2012017
National Heart, Lung, and Blood Institute (NHLBI)Government2012017
Assistance Publique - Hôpitaux de ParisAcademic/Hospital1112018
Blood and Marrow Transplant Clinical Trials NetworkAcademic/Hospital1012017
Center for International Blood and Marrow Transplant ResearchGovernment1012017
Cohen Children's Medical Center of New YorkAcademic/Hospital1012014
Cornell UniversityAcademic/Hospital1112012
Fujian Medical UniversityAcademic/Hospital1012024
Government of ChinaGovernment1012012
Government of PakistanGovernment1112018
Huazhong University of Science and TechnologyAcademic/Hospital1012024
Isfahan UniversityAcademic/Hospital1112006
Lund UniversityAcademic/Hospital1112005
National Institute of Allergy and Infectious Diseases (NIAID)Government1112014
National Marrow Donor ProgramGovernment1012017
New York Blood CenterAcademic/Hospital1012014
29 organizations
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