cd123 car-t cells
Cell therapyexperimental
Clinical trial activity
17 trials · 19 clinical orgs · 0 marketing orgs
Phase 1
16
Phase 2
7
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2016 (NCT02937103)
Timeline
2010s
- Jan 1, 2016
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Drugs, Investigational · Phase 1/Phase 2
- Leukemia · Phase 1/Phase 2
- Leukemia, Lymphoid · Phase 1
- Leukemia, Myeloid · Phase 1/Phase 2
- Leukemia, Myeloid, Acute · Phase 1/Phase 2
- Myelodysplastic Syndromes · Early Phase 1
- Neoplasms · Phase 1/Phase 2
- Plasmacytoma · Early Phase 1
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Early Phase 1
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
Mechanism of action
- Interleukin-3 receptor subunit alphaImmunity, passive
IL3RA immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-cd123-car t cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07201727 | Early Phase 1 (Phase 1) | Sep 30, 2025 | China Academy of Chinese Medical Sciences |
| NCT06917105 | Phase 1/Phase 2 (Phase 2) | Apr 1, 2025 | Government of China, Huazhong University of Science and Technology |
| NCT06768476 | Phase 1 | Feb 28, 2025 | Novartis, University of Pennsylvania |
| NCT06765876 | Early Phase 1 (Phase 1) | Oct 23, 2024 | Institute of Hematology and Blood Transfusion, Czech Republic |
| NCT06420063 | Phase 1/Phase 2 (Phase 2) | Jul 10, 2024 | Essen Biotech |
| NCT04678336 | Phase 1 | Jan 31, 2021 | University of Pennsylvania |
| NCT04318678 | Phase 1 | Apr 30, 2020 | St. Jude Children's Hospital |
| NCT04272125 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2019 | Chongqing Medical University, Chongqing Precision Biotech Co., Ltd |
| NCT04265963 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2019 | Chongqing Medical University, Chongqing Precision Biotech Co., Ltd, People's Liberation Army of China |
| NCT04010877 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2019 | Shenzhen Geno-Immune Medical Institute |
| NCT03796390 | Phase 1 | Dec 26, 2018 | Hebei Senlang Biotechnology Inc., Ltd., Ludaopei Hospital |
| NCT03766126 | Phase 1 | Dec 6, 2018 | University of Pennsylvania |
| NCT03672851 | Phase 1 | Sep 17, 2018 | GenScript, Jiao Tong University |
| NCT03585517 | Phase 1 | Jul 21, 2018 | Beijing Immunochina Medical Science & Technology Co., Ltd. |
| NCT03473457 | N/A | Apr 1, 2018 | Southern Medical University, Sun Yat-Sen University |
| NCT03556982 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2018 | People's Liberation Army of China |
| NCT02937103 | Phase 1/Phase 2 (Phase 2) | Oct 1, 2016 | People's Liberation Army of China |
Showing 17 of 17 trials
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Organizations
Research & Development (19)
19 organizations
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