CDEK
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isopropyl alcohol

Small moleculeapproved

Approved

Jul 14, 2000

Isopropanolamine (1-Amino-2-propanol) is a colorless to yellowish liquid with an amine-like odor. It is miscible in water. Intermediate used in the production of dyes, lubrification oils, corrosion inhibitor, detergents, cutting fluids. — NCATS

Clinical trial activity

47 trials · 52 clinical orgs · 6 marketing orgs

Phase 1
4
Phase 2
19
Phase 3
13
Phase 4
12

Earliest trial started May 1, 2002 (NCT00515151)

Timeline

1950s

  1. Jun 1, 1954

    Evidence of US Marketing

2000s

  1. Jul 14, 2000

    Earliest FDA Approval

  2. Jul 14, 2000

    Becton Dickinson — NDA Secondary Org

  3. Jun 3, 2005

    PDI Healthcare — NDA Secondary Org

  4. Sep 29, 2006

    3M — NDA Secondary Org

  5. Sep 29, 2006

    Graceway — NDA Secondary Org

  6. Jan 1, 2007

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2015

    3M — Earliest Phase 2 Sponsor(trial)

  3. Aug 8, 2018

    Bausch Health Companies — NDA Secondary Org

  4. Apr 26, 2019

    Zurex Pharma, Inc. — Marketing Organization

  5. Apr 26, 2019

    Zurex Pharma, Inc. — NDA Secondary Org

Indications

Approved for

Studied for

Mechanism of action

Combination products

  • chloraprep one-step

    with chlorhexidine

    Also known as chloraprep one-step frepp, chloraprep one-step sepp, chloraprep single swabstick, chloraprep triple swabstick, chloraprep with tint, prevantics maxi swabstick, prevantics swab, prevantics swabstick

  • duraprep

    with iodine povacrylex

Approval history

  • approvedJul 14, 2000
  • approvedJun 1, 1954

Chemistry & pharmacology

Loading structure…

SMILES

CC(C)O
Mol. weight
60.095 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Topical
Availability
Over the Counter

Oral

No

Parenteral

No

Topical

Yes

Sources

Also known as

  • 2-propanol
  • 2-propanol
  • 2-propanol
  • 2-propanol
  • chlorhexidine gluconate mixture with isopropyl alcohol
  • duraprep
  • ipa
  • ipa
  • ipa
  • isopropanol
  • isopropanol
  • isopropanol
  • isopropanol
  • isopropanol
  • isopropanol
  • iso-propanol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • isopropyl alcohol
  • manugel
  • manugel
  • medi-swab
  • medi-swab h
  • riboprine
  • riboprine
  • sterets
  • sterets h
  • swim-ear

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06836271Phase 2Mar 1, 2025Hitit University
NCT05920122Phase 4Oct 9, 2023University of Pittsburgh
NCT05418244Phase 2/Phase 3 (Phase 3)Apr 20, 2022State University of New York, Buffalo
NCT05401292Phase 4Feb 15, 2022University of Missouri
NCT05175521N/ANov 11, 2021HonorHealth Research Institute
NCT04756804Phase 3Jun 21, 2021Medical College of Wisconsin, Zurex Pharma, Inc.
NCT04464915N/AJul 31, 2020University of Ottawa
NCT04756154Phase 3Jul 6, 20203M, Microbac
NCT04307550Phase 1/Phase 2 (Phase 2)Jun 19, 2020University of Calgary
NCT04218110Phase 3Feb 11, 2020Eurofins, PDI Healthcare
NCT04181463N/AJan 31, 2020National Cancer Institute (NCI), University of Texas at Houston
NCT03859908Phase 4Apr 5, 2019Universidad del Salvador
NCT03782103Phase 3Jan 25, 2019Zurex Pharma, Inc.
NCT06733506Phase 4Oct 1, 2018University of Illinois at Chicago
NCT03489512Phase 4Oct 1, 2018University of Valencia
NCT03691831Phase 3Sep 17, 2018Aclaris Therapeutics, Inc.
NCT03560193Phase 4Sep 10, 2018University of Poitiers
NCT03523962Phase 3Aug 21, 2018McMaster University, Patient-Centered Outcomes Research Institute, University of Maryland
NCT03417661Phase 3Jun 29, 2018Gama Healthcare Ltd.
NCT03224299Phase 2Jun 21, 2017Becton Dickinson
Showing 20 of 47 trials
Page 1 / 3

Organizations

Research & Development (52)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
3MFor profit11842010
MicroBioTestFor profit4032011
CareFusionFor profit3322007
Universidad de GuanajuatoAcademic/Hospital2212011
Zurex Pharma, Inc.For profit2212019
Aclaris Therapeutics, Inc.For profit1112018
Antisepsia CentralAcademic/Hospital1012011
Becton DickinsonFor profit1112017
Bio-Science LaboratoriesFor profit1012013
Case Western Reserve UniversityAcademic/Hospital1112014
Centers for Disease Control and Prevention (CDC)Government1012012
Cyberderm Inc.For profit1012010
EurofinsFor profit1012020
Gama Healthcare Ltd.For profit1112018
Hitit UniversityAcademic/Hospital1112025
HonorHealth Research InstituteAcademic/Hospital1112021
Icahn School of Medicine at Mount SinaiAcademic/Hospital1012011
Johns Hopkins UniversityAcademic/Hospital1112008
Johnson and JohnsonFor profit1112015
Lakehead UniversityAcademic/Hospital1112014
52 organizations
Page 1 / 3

Marketing (9)

OrganizationOrg typeRelationshipDate
3MFor profitNDA—
3MFor profitNDA2Sep 29, 2006
3MFor profitSYNAug 8, 2018
Bausch Health CompaniesFor profitNDA2Aug 8, 2018
Becton DickinsonFor profitNDA2Jul 14, 2000
GracewayFor profitNDA2Sep 29, 2006
PDI HealthcareFor profitNDA2Jun 3, 2005
Zurex Pharma, Inc.For profitMKTGApr 26, 2019
Zurex Pharma, Inc.For profitNDA2Apr 26, 2019