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Malaria, Falciparum
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
Subtype terms (1)
More specific conditions that are subtypes of Malaria, Falciparum in the MeSH hierarchy.
Drugs by status
Approved for this indication (6)
Phase 4 trials (19)
Phase 3 trials (13)
Phase 2 trials (47)
- dsm265
- ferroquine
- fosmidomycin
- imatinib
- cipargamin
- meningococcal (groups A, C, Y, W) CRM197 conjugate vaccine
- momordica charantia
- montanide isa 720
- mva me-trap
- pfcs102
- aluminum hydroxide
- methylene blue
- sitagliptin
- (+)-sj000557733
- tafenoquine succinate
- clonidine
- pentoxifylline
- hepatitis a vaccine, inactivated
- ama1
- fp9 me-trap
- fp9-pp
- mva cs
- mva-pp
- pev3a
- pfspz
- sevuparin
- chad63
- me-trap
- pfs25-imx313
- falciparum malaria protein 11
- +17 more
Phase 1 trials (44)
- sodium nitrite
- gsk3191607
- monoaluminum phosphate
- bacille calmette-guerin
- ad35.cs.01
- eba-175 rii-ng malaria vaccine
- ep-1300
- gap3ko
- imiquimod
- mepolizumab
- mmv390048
- rabies vaccine (purified chick embryo cell vaccine)
- yellow fever vaccine 17d strain
- ama1-c1
- ap10-602
- chad63 rh5
- cpg 7909 oligodeoxynucleotide
- malaria icc-1132
- malaria transmission-blocking pfs25-pfs25 conjugate vaccine
- mva rh5
- pev301
- pfama-1-fvo[25-545]
- pfcsp dna (vcl-2510) vaccine
- plasmodium falciparum sporozoite
- virosomal influenza vaccine
- virosome-formulated synthetic malaria peptides
- ama1-dico
- moxifloxacin
- msp1(42)-fvo
- msp1(42)-3d7
- +14 more
Other trials (3)
Organizations
Organization Involved with Phase 4 Indications (67)
- Pfizer
- Sanofi
- Novartis
- Institut Pasteur
- Dafra Pharma
- Epicentre
- Bandim Health Project
- Malaria Consortium
- Medicines for Malaria Venture
- National Institutes of Health (NIH)
- Medical Research Council
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute for Medical Research, Tanzania
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institute of Malariology, Parasitology and Entomology, Vietnam
- United States Navy
- World Health Organization
- Centre Muraz
- University of London
- Duke University
- Institute of Tropical Medicine, Belgium
- Ifakara Health Institute
- Instituto Nacional de Salud. Peru
- Kenya Medical Research Institute
- Mahidol University
- Menzies School of Health Research
- Radboud University
- University of Liverpool
- Yale University
- Bernhard Nocht Institute for Tropical Medicine
- +37 more
Organization Involved with Phase 3 Indications (38)
- Proto Pharma Ltd
- Tropical Diseases Research Centre, Zambia
- Pan American Health Organization
- Centro Internacional de Entrenamiento e Investigaciones Médicas
- Johns Hopkins University
- University of Khartoum
- University of Bamako
- University of Bamenda
- Department of Medical Research, Lower Myanmar
- University of British Columbia
- University of Nairobi
- University of Basel
- Xidea Solutions Ltd
- Government of Pakistan
- Government of China
- University of Sao Paulo
- University of Barcelona
- Clinical Research Unit Nanoro
- Medical Research Council, The Gambia
- Cambodia National Malaria Control Programme
- Kigali Central University Hospital, Rwanda
- HealthNet International, Peshawar, Pakistan
- European and Developing Countries Clinical Trials Partnership (EDCTP)
- University of the Sciences, Techniques and Technologies of Bamako
- Government of Brazil
- HealthNet TPO
- University of Calabar
- Government of Afghanistan
- Government of Tanzania
- Government of Uganda
- +8 more
Organization Involved with Phase 2 Indications (54)
- Zentopharm GmbH
- HuLow
- Leadiant Biosciences, Inc.
- Mepha Ltd.
- Modus Therapeutics AB
- Sanaria Inc.
- Jomaa Pharma GmbH
- Pevion Biotech Ltd
- United States Army
- Albert Schweitzer Hospital
- European Malaria Vaccine Initiative
- Jimma University
- Marquette University
- Thammasat University
- University of Heidelberg
- University of Lausanne
- University of Maryland
- University of Sydney
- University of Toronto
- Vinmec International Hospital
- Centre de Recherche Médicale de Lambaréné
- Purdue University
- University of Utah
- University of Vienna
- Leiden University
- International Center for Diarrheal Disease Research
- Hue University
- Ranbaxy
- University of Turin
- University of Gondar
- +24 more
Organization Involved with Phase 1 Indications (31)
- FGK Clinical Research GmbH
- Immune Design
- Mymetics Corporation
- Shanghai Wanxing Bio-Pharmaceutical Co. Ltd.
- Deakin University
- Institut National de la Santé Et de la Recherche Médicale, France
- Tulane University
- University of South Florida
- University of Cape Town
- Hammersmith Medicines Research
- SGS Life Sciences
- Jiao Tong University
- University of Queensland
- Q-Pharm
- Clinical Neuroscience Solutions, Inc.
- University of Paris
- Centre National de Recherche et de Formation sur la Paludisme, Ouagadougou, Burkina Faso
- ICON
- CPR Pharma Services Pty Ltd, Australia
- German Federal Ministry of Education and Research
- Medical Care Development, Inc.
- Charles Mérieux Center for Infectious Disease, Mali
- Biomedical Primate Research Centre
- SEPPIC, Paris
- People's Liberation Army of China
- Comprehensive Clinical Development, Inc.
- IQVIA
- PTx Solutions
- PrimeVigilance LTD
- Swiss BioQuant A.G., Switzerland
- +1 more
Organization Involved with Other Experimental Indications (22)
- FHI 360
- Global Emerging Infections Surveillance and Response System
- Swiss Federal Institute of Technology
- Armed Forces Research Institute of Medical Sciences, Thailand
- Gadjah Mada University
- Myanmar Oxford Clinical Research Unit
- Department of Defense
- Research Institute for Tropical Medicine, Alabang, Muntinlupa, Metro Manila, Philippines
- National Malaria Control Programme Cambodia
- Kilimanjaro Christian Medical College, Tanzania
- RITM, DOH, Philippines
- Department of Veteran Affairs
- Bill and Melinda Gates Foundation
- Eijkman Institute for Molecular Biology, Jakarta, Indonesia
- Timika Research Facility, Indonesia
- Family Health International, Cambodia
- National Malaria Control Program, Vietnam
- National Malaria Control Program, Myanmar
- Royal Cambodian Armed Forces
- Li Ka Shing Foundation
- Department of Health, Philippines
- Government of Zambia