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matrix m1

Vaccineexperimental

Clinical trial activity

61 trials · 41 clinical orgs · 0 marketing orgs

Phase 1
37
Phase 2
30
Phase 3
9
Phase 4
2

Earliest trial started Aug 1, 2008 (NCT00942071)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • UnclearImmunity, active

    Unclear immunity, active

Chemistry & pharmacology

Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • matrix m
  • matrix m1
  • matrix-m1
  • rotavin-m1

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07194668Phase 4Dec 1, 2025University of Oxford
NCT07183371Phase 2Nov 30, 2025European and Developing Countries Clinical Trials Partnership (EDCTP), European Vaccine Initiative (EVI), Heidelberg, Germany, Government of Germany, Institut et Haute école de la Santé, La Source, University of Oxford
NCT06958198Phase 1Sep 15, 2025European and Developing Countries Clinical Trials Partnership (EDCTP), European Vaccine Initiative (EVI), Heidelberg, Germany, Government of Germany, Institut et Haute école de la Santé, La Source, University of Oxford, Wellcome Trust
NCT07147400Phase 2Aug 22, 2025National Institute of Allergy and Infectious Diseases (NIAID), Serum Institute of India Pvt. Ltd.
NCT06816524N/AJul 1, 2025Jomo Kenyatta University of Agriculture and Technology, National Institute for Public Health and the Environment, RIVM, Holland, Radboud University, Swiss Federal Institute of Technology
NCT06080243Phase 2Feb 1, 2025European Vaccine Initiative (EVI), Heidelberg, Germany, Malaria Research and Training Center, Bamako, Mali, University of Oxford
NCT06482359Phase 2/Phase 3 (Phase 3)Nov 1, 2024Novavax
NCT06291857Phase 3Oct 21, 2024Novavax
NCT06320535Phase 1Mar 25, 2024Bill and Melinda Gates Foundation, University Hospitals Bristol NHS Foundation Trust, University of Oxford
NCT06068530Phase 4Nov 1, 2023Mahidol University, University of Oxford
NCT05683834Phase 1/Phase 2 (Phase 2)Sep 22, 2023National Institute of Allergy and Infectious Diseases (NIAID)
NCT05978037Phase 1/Phase 2 (Phase 2)Aug 18, 2023University of Oxford
NCT05913973Phase 1Aug 4, 2023National Institute of Allergy and Infectious Diseases (NIAID)
NCT06141057Phase 1Jun 6, 2023University of Oxford
NCT05790889Phase 1/Phase 2 (Phase 2)Apr 3, 2023European and Developing Countries Clinical Trials Partnership (EDCTP), Institut et Haute école de la Santé, La Source, University of Oxford, Wellcome Trust
NCT05875701Phase 3Mar 28, 2023Novavax
NCT05357560Phase 1Feb 28, 2023European and Developing Countries Clinical Trials Partnership (EDCTP), Medical Research Council, The Gambia, University of Oxford
NCT05519839Phase 2Jan 16, 2023Novavax
NCT05400746Early Phase 1 (Phase 1)Nov 2, 2022University of Oxford
NCT05385471Early Phase 1 (Phase 1)Nov 1, 2022Churchill Hospital, Oxford, University of Oxford
Showing 20 of 61 trials
Page 1 / 4

Organizations

Research & Development (41)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of OxfordAcademic/Hospital363342008
NovavaxFor profit141332014
Wellcome TrustAcademic/Hospital5032008
Barinthus BiopharmaceuticalsFor profit4422017
European and Developing Countries Clinical Trials Partnership (EDCTP)Academic/Hospital4022023
Institut et Haute école de la Santé, La SourceAcademic/Hospital4032021
National Institute of Allergy and Infectious Diseases (NIAID)Government4322021
European Vaccine Initiative (EVI), Heidelberg, GermanyGovernment3122025
Government of VietnamGovernment3222009
Ifakara Health InstituteAcademic/Hospital3022020
Malaria Research and Training Center, Bamako, MaliAcademic/Hospital3032021
Bill and Melinda Gates FoundationAcademic/Hospital2022020
Churchill Hospital, OxfordAcademic/Hospital2012022
Department of Health and Human ServicesGovernment2022014
Government of GermanyGovernment2022025
Mahidol UniversityAcademic/Hospital2022022
University of LondonAcademic/Hospital2012020
Center for Research and Production of Vaccines and Biologicals, VietnamAcademic/Hospital1112019
Centre National de Recherche et de Formation sur la Paludisme, Ouagadougou, Burkina FasoAcademic/Hospital1012016
Clinical Network ServicesFor profit1012019
41 organizations
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