PDCD1

SINGLE PROTEINHomo sapiens

Preferred name: Programmed cell death protein 1 ChEMBL ↗

Linked proteins

Programmed cell death protein 1 (PDCD1) ↗

Drugs acting on this target (123)

Active Pharmaceutical Ingredient	Mechanism Type ▲	Approval Status	API Type	Mechanism of Action
gs-0151	Agonist	experimental	Small molecule	PDCD1 agonist
rosnilimab	Agonist	experimental	mAb	PD1
ak105	Antagonist	experimental	mAb	PD1
AZD2936	Antagonist	experimental	mAb	PD1
azd7789	Antagonist	experimental	mAb	PD1
balstilimab	Antagonist	experimental	mAb	PD1
bat1308	Antagonist	experimental	mAb	PD1
bat7104	Antagonist	experimental	mAb	PD1
caldonirimab	Antagonist	experimental	mAb	PD1
camrelizumab	Antagonist	experimental	mAb	PDCD1 antagonist
dostarlimab (Jemperli)	Antagonist	approved	mAb	Programmed cell death protein 1 antagonist
evt801	Antagonist	experimental	mAb	PD1
hlx10	Antagonist	experimental	mAb	Programmed cell death protein 1 antagonist
HX-008	Antagonist	experimental	mAb	PD1
IBI319	Antagonist	experimental	mAb	PD1
ibi321	Antagonist	experimental	mAb	PD1
inca32459-101	Antagonist	experimental	mAb	PD1
lb1410	Antagonist	experimental	mAb	pd1
lbl-015	Antagonist	experimental	mAb	PD1
lbl-019	Antagonist	experimental	mAb	PD1
lm-108	Antagonist	experimental	mAb	PDCD1 antagonist
lvgn3616	Antagonist	experimental	mAb	PD1
palivizumab (Synagis)	Antagonist	approved	mAb	PD1
penpulimab	Antagonist	approved	mAb	PD1
pf-07225570	Antagonist	experimental	mAb	PD1
retifanlimab (Zynyz)	Antagonist	approved	mAb	PDCD1 antagonist
sasanlimab	Antagonist	experimental	mAb	Programmed cell death protein 1 antagonist
si-b003	Antagonist	experimental	mAb	PD1
sintilimab	Antagonist	experimental	mAb	PDCD1 antagonist
spartalizumab	Antagonist	experimental	mAb	Programmed cell death protein 1 antagonist
ssgj-705	Antagonist	experimental	mAb	PD1
tirelizumab	Antagonist	experimental	mAb	PD1
toripalimab (LOQTORZ)	Antagonist	approved	mAb	PDCD1 antagonist
tqb2868	Antagonist	experimental	mAb	PD1
zg005	Antagonist	experimental	mAb	PDCD1 antagonist
zimberelimab	Antagonist	experimental	mAb	PD1
ph-762	Antisense inhibitor	experimental	Nucleic acid	PDCD1 antisense inhibitor
imu-201	Immunity, active	experimental	Vaccine	PDCD1 immunity, active
αpd1-msln-car t cells	Immunity, passive	experimental	Cell therapy	PDCD1 immunity, passive
89zr-pembrolizumab	Inhibitor	experimental	mAb	PDCD1 inhibitor
ak-104	Inhibitor	experimental	mAb	PDCD1 inhibitor
ak112	Inhibitor	experimental	mAb	PDCD1 inhibitor
ak131	Inhibitor	experimental	mAb	PDCD1 inhibitor
amg 256	Inhibitor	experimental	mAb	PDCD1 inhibitor
amp-224	Inhibitor	experimental	mAb	PDCD1 inhibitor
anv600	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
apl-501	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
askg915	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
awt020	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
bc008	Inhibitor	experimental	mAb	PDCD1 inhibitor
bcd-217	Inhibitor	experimental	mAb	PDCD1 inhibitor
bpt567	Inhibitor	experimental	mAb	PDCD1 inhibitor
budigalimab	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
cadonilimab	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
cd-001	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
cdx-527	Inhibitor	experimental	mAb	PDCD1 inhibitor
cemiplimab (libtayo)	Inhibitor	approved	mAb	Programmed cell death protein 1 inhibitor
cetrelimab	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
cm310	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
copper cu 64-dota-pembrolizumab	Inhibitor	experimental	mAb	PDCD1 inhibitor
cr-001	Inhibitor	experimental	mAb	PDCD1 inhibitor
cs2009	Inhibitor	experimental	mAb	PDCD1 inhibitor
ct011	Inhibitor	experimental	mAb	PDCD1 inhibitor
ctx-10726	Inhibitor	experimental	mAb	PDCD1 inhibitor
ctx-8371	Inhibitor	experimental	mAb	PDCD1 inhibitor
dv281	Inhibitor	experimental	mAb	PDCD1 inhibitor
emb-02	Inhibitor	experimental	mAb	PDCD1 inhibitor
enlonstobart	Inhibitor	experimental	mAb	PDCD1 inhibitor
fp008	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
gb268	Inhibitor	experimental	mAb	PDCD1 inhibitor
gensci120	Inhibitor	experimental	mAb	PDCD1 inhibitor
hbt-708	Inhibitor	experimental	mAb	PDCD1 inhibitor
hlx17	Inhibitor	experimental	mAb	PDCD1 inhibitor
hx008	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
hx009	Inhibitor	experimental	mAb	PDCD1 inhibitor
iap0971	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
ibi315	Inhibitor	experimental	mAb	PDCD1 inhibitor
ibi318	Inhibitor	experimental	mAb	PDCD1 inhibitor
icon-1	Inhibitor	experimental	mAb	PDCD1 inhibitor
inca33890	Inhibitor	experimental	mAb	PDCD1 inhibitor
iparomlimab	Inhibitor	experimental	mAb	PDCD1 inhibitor
jmt108	Inhibitor	experimental	mAb	PDCD1 inhibitor
js201	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
js207	Inhibitor	experimental	mAb	PDCD1 inhibitor
ky-0118	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
lerapolturev	Inhibitor	experimental	Small molecule	PDCD1 inhibitor
lm-299	Inhibitor	experimental	mAb	PDCD1 inhibitor
lvgn 3616	Inhibitor	experimental	mAb	PDCD1 inhibitor
maq-001	Inhibitor	experimental	Biological	PDCD1 inhibitor
medi5752	Inhibitor	experimental	mAb	PDCD1 inhibitor
mgd013	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
mgd019	Inhibitor	experimental	mAb	PDCD1 inhibitor
mhb039a	Inhibitor	experimental	mAb	PDCD1 inhibitor
nivolumab (opdivo)	Inhibitor	approved	mAb	PDCD1 inhibitor
ono-4685	Inhibitor	experimental	mAb	PDCD1 inhibitor
ono-7018	Inhibitor	experimental	mAb	PDCD1 inhibitor
p1801	Inhibitor	experimental	mAb	PDCD1 inhibitor
pd-1/ctla-4 dual functional antibody	Inhibitor	experimental	mAb	PDCD1 inhibitor
pe0105	Inhibitor	experimental	mAb	PDCD1 inhibitor
pembrolizumab (keytruda)	Inhibitor	approved	mAb	PDCD1 inhibitor
penpulimab	Inhibitor	approved	mAb	Programmed cell death protein 1 inhibitor
pidilizumab	Inhibitor	experimental	mAb	PDCD1 inhibitor
Prolgolimab	Inhibitor	experimental	mAb	PDCD1 inhibitor
psb205	Inhibitor	experimental	mAb	PDCD1 inhibitor
ql-1706	Inhibitor	experimental	mAb	PDCD1 inhibitor
ql1604	Inhibitor	experimental	mAb	PDCD1 inhibitor
ql1706	Inhibitor	experimental	mAb	PDCD1 inhibitor
regn10597	Inhibitor	experimental	mAb	PDCD1 inhibitor
ro7121661	Inhibitor	experimental	mAb	PDCD1 inhibitor
ro7247669	Inhibitor	experimental	mAb	PDCD1 inhibitor
ro7284755	Inhibitor	experimental	mAb	PDCD1 inhibitor
s-4321	Inhibitor	experimental	mAb	PDCD1 inhibitor
sar445877	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
shr-1901	Inhibitor	experimental	mAb	PDCD1 inhibitor
shr-5495	Inhibitor	experimental	mAb	PDCD1 inhibitor
sindilizumab	Inhibitor	experimental	mAb	PDCD1 inhibitor
sot201	Inhibitor	experimental	Recombinant protein	PDCD1 inhibitor
sysa1802	Inhibitor	experimental	mAb	PDCD1 inhibitor
tislelizumab	Inhibitor	approved	mAb	PDCD1 inhibitor
xmab20717	Inhibitor	experimental	mAb	PDCD1 inhibitor
xmab23104	Inhibitor	experimental	mAb	PDCD1 inhibitor
zimberelimab	Inhibitor	experimental	mAb	Programmed cell death protein 1 inhibitor
sl-279252	Supplementation	experimental	Recombinant protein	PDCD1 supplementation