← Mechanisms of action
Voltage-gated calcium channel
PROTEIN COMPLEX GROUPHomo sapiens
Linked proteins
- Voltage-dependent T-type calcium channel subunit alpha-1H (CACNA1H) ↗
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1) ↗
- Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) ↗
- Voltage-dependent calcium channel subunit alpha-2/delta-3 (CACNA2D3) ↗
- Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S) ↗
- Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2) ↗
- Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D) ↗
- Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A) ↗
- Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B) ↗
- Voltage-dependent T-type calcium channel subunit alpha-1G (CACNA1G) ↗
- Voltage-dependent calcium channel subunit alpha-2/delta-4 (CACNA2D4) ↗
- Voltage-dependent T-type calcium channel subunit alpha-1I (CACNA1I) ↗
- Voltage-dependent L-type calcium channel subunit alpha-1F (CACNA1F) ↗
- Voltage-dependent R-type calcium channel subunit alpha-1E (CACNA1E) ↗
- Voltage-dependent L-type calcium channel subunit beta-3 (CACNB3) ↗
- Voltage-dependent calcium channel gamma-7 subunit (CACNG7) ↗
- Voltage-dependent calcium channel gamma-5 subunit (CACNG5) ↗
- Voltage-dependent calcium channel gamma-2 subunit (CACNG2) ↗
- Voltage-dependent L-type calcium channel subunit beta-4 (CACNB4) ↗
- Voltage-dependent L-type calcium channel subunit beta-2 (CACNB2) ↗
- Voltage-dependent L-type calcium channel subunit beta-1 (CACNB1) ↗
- Voltage-dependent calcium channel gamma-4 subunit (CACNG4) ↗
- Voltage-dependent calcium channel gamma-8 subunit (CACNG8) ↗
- Voltage-dependent calcium channel gamma-3 subunit (CACNG3) ↗
- Voltage-dependent calcium channel gamma-6 subunit (CACNG6) ↗
- Voltage-dependent calcium channel gamma-1 subunit (CACNG1) ↗
Drugs acting on this target (14)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| nivaldipine | Antagonist | experimental | Small molecule | Voltage-gated calcium channel antagonist |
| s-licarbazepine | Antagonist | experimental | Small molecule | Voltage-gated calcium channel antagonist |
| bepridil (vascor) | Blocker | approved | Small molecule | Voltage-gated calcium channel blocker |
| phloroglucinol | Blocker | experimental | Small molecule | Voltage-gated calcium channel blocker |
| suloctidil | Blocker | experimental | Small molecule | Voltage-gated calcium channel blocker |
| terodiline | Blocker | experimental | Small molecule | Voltage-gated calcium channel blocker |
| cinepazide | Inhibitor | experimental | Small molecule | Voltage-gated calcium channel inhibitor |
| eperisone | Inhibitor | experimental | Small molecule | Voltage-gated calcium channel inhibitor |
| gw273225 | Inhibitor | experimental | Small molecule | Voltage-gated calcium channel inhibitor |
| phloroglucinol | Inhibitor | experimental | Small molecule | Voltage-gated calcium channel inhibitor |
| atagabalin | Modulator | experimental | Small molecule | Voltage-gated calcium channel modulator |
| gabapentin (neurontin) | Modulator | approved | Small molecule | Voltage-gated calcium channel modulator |
| imagabalin | Modulator | experimental | Small molecule | Voltage-gated calcium channel modulator |
| pregabalin (lyrica) | Modulator | approved | Small molecule | Voltage-gated calcium channel modulator |