← Mechanisms of action
Voltage-gated T-type calcium channel
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (16)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ad-101 | Agonist | experimental | Small molecule | Voltage-gated T-type calcium channel agonist |
| azelnidipine | Antagonist | experimental | Small molecule | Voltage-gated T-type calcium channel antagonist |
| manidipine | Antagonist | experimental | Small molecule | Voltage-gated T-type calcium channel antagonist |
| mk-8998 | Antagonist | experimental | Small molecule | Voltage-gated T-type calcium channel antagonist |
| Apinocaltamide | Blocker | experimental | Small molecule | Voltage-gated T-type calcium channel blocker |
| ethosuximide (zarontin) | Blocker | approved | Small molecule | Voltage-gated T-type calcium channel blocker |
| methsuximide (celontin) | Blocker | approved | Small molecule | Voltage-gated T-type calcium channel blocker |
| mibefradil (Posicor) | Blocker | withdrawn | Small molecule | Voltage-gated T-type calcium channel blocker |
| paramethadione (Paradione) | Blocker | approved | Small molecule | Voltage-gated T-type calcium channel blocker |
| phensuximide (milontin) | Blocker | approved | Small molecule | Voltage-gated T-type calcium channel blocker |
| trimethadione (tridione) | Blocker | approved | Small molecule | Voltage-gated T-type calcium channel blocker |
| abt-639 | Inhibitor | experimental | Small molecule | Voltage-gated T-type calcium channel inhibitor |
| act-280778 | Inhibitor | experimental | Small molecule | Voltage-gated T-type calcium channel inhibitor |
| Apinocaltamide | Inhibitor | experimental | Small molecule | Voltage-gated T-type calcium channel inhibitor |
| prax-944 | Inhibitor | experimental | Small molecule | Voltage-gated T-type calcium channel inhibitor |
| Suvecaltamide | Modulator | experimental | Small molecule | Voltage-gated T-type calcium channel modulator |