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nivaldipine

Small moleculeexperimental

Clinical trial activity

1 trials · 15 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
1
Phase 3
1
Phase 4
0

Earliest trial started Apr 24, 2013 (NCT02017340)

Timeline

2010s

  1. Jan 1, 2013

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COC(=O)C1=C(C#N)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1
Mol. weight
385.38 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 3,5-pyridinedicarboxylic acid, 2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester
  • 5-isopropyl-3-methyl-2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinecarboxylate
  • cl-287389
  • cl-287389
  • dolorgiet brand of nilvadipine
  • escor
  • fk-235
  • fk-235
  • fr 34235
  • fr-34235
  • fr-34235
  • fr-34235
  • fr-34235
  • fr-34235
  • fr-34235
  • klinge brand of nilvadipine
  • nilvadipine
  • nilvadipine
  • nilvadipine
  • nilvadipine
  • nilvadipine
  • nilvadipine
  • nilvadipine
  • nivadil
  • nivadil
  • nivadil
  • nivadil
  • nivadipine
  • nivadipine
  • nivaldipine
  • sk&f-102362
  • sk&f-102362
  • trommsdorff brand of nilvadipine

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02017340Phase 3Apr 24, 2013Alzheimer Europe, Archer Pharmaceuticals, Inc., Aristotle University of Thessaloniki, E-Search Limited, Goeteborgs Universitet, Katholieke Universiteit Leuven, Mario Negri Institute, Molecular Medicine Ireland LBG, National University of Ireland, St. James's Hospital, Ireland, Szeged University, Trinity College Dublin, University of Lille, University of London, University of Ulm
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (15)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Alzheimer EuropeAcademic/Hospital1012013
Archer Pharmaceuticals, Inc.For profit1012013
Aristotle University of ThessalonikiAcademic/Hospital1012013
E-Search LimitedFor profit1012013
Goeteborgs UniversitetAcademic/Hospital1012013
Katholieke Universiteit LeuvenAcademic/Hospital1012013
Mario Negri InstituteAcademic/Hospital1012013
Molecular Medicine Ireland LBGAcademic/Hospital1012013
National University of IrelandAcademic/Hospital1012013
St. James's Hospital, IrelandAcademic/Hospital1112013
Szeged UniversityAcademic/Hospital1012013
Trinity College DublinAcademic/Hospital1012013
University of LilleAcademic/Hospital1012013
University of LondonAcademic/Hospital1012013
University of UlmAcademic/Hospital1012013
15 organizations
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