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phloroglucinol

Small moleculeexperimental

Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isomers are hydroxyquinol (1,2,4-benzenetriol) and pyrogallol (1,2,3-benzenetriol). Phloroglucinol, and its benzenetriol isomers, are still defined as "phenols" according to the IUPAC official nomenclature rules of chemical compounds. Many such monophenolics are often termed polyphenols. The enzyme is biosynthesized by phloroglucinol synthase. — Wikipedia

Clinical trial activity

4 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
3
Phase 3
2
Phase 4
1

Earliest trial started Dec 1, 2009 (NCT01842932)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 3 Sponsor(trial)

2020s

  1. Jan 1, 2023

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Oc1cc(O)cc(O)c1
Mol. weight
126.11 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1,3,5-benzenetriol
  • 1,3,5-benzenetriol - 1,3,5-trimethoxybenzene
  • 1,3,5-benzenetriol, 1,3,5-trimethoxybenzene drug combination
  • 1,3,5-benzenetriol, mixt. with 1,3,5-trimethoxybenzene
  • phloroglucin
  • phloroglucin
  • phloroglucin
  • phloroglucin
  • phloroglucine
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • phloroglucinol
  • spasfon
  • spasfon
  • spasfon
  • spasfon-lyoc
  • spasfon-lyoc

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06153420Phase 2Dec 25, 2023CinRx Pharma
NCT03342118Phase 3Sep 21, 2017Keimyung University
NCT01061073Phase 3Jan 1, 2010University of Poitiers
NCT01842932Phase 4Dec 1, 2009Ajou University
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Ajou UniversityAcademic/Hospital1112009
CinRx PharmaFor profit1112023
Keimyung UniversityAcademic/Hospital1112017
University of PoitiersAcademic/Hospital1112010
4 organizations
Page 1 / 1