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cinepazide

Small moleculeexperimental

Cinepazide or cinepazide maleate is a vasodilator used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. It appears to work by potentiating A2 adenosine receptors. — Wikipedia

Clinical trial activity

3 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Jul 1, 2008 (NCT01831011)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COc1cc(/C=C/C(=O)N2CCN(CC(=O)N3CCCC3)CC2)cc(OC)c1OC
Mol. weight
417.51 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1-((1-pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine
  • 1-((1-pyrrolidynylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine maleate
  • 67350-md
  • 67350-md
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide
  • cinepazide maleate
  • cinepazide maleate
  • cinepazide maleate
  • cinepazide maleate
  • cinepazide maleate
  • md-67350 [as maleate]
  • md-67350 [as maleate]
  • vasodistal
  • vasodistal
  • vasodistal

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04951232N/AJul 4, 2016Chinese Academy of Medical Sciences, Peking University
NCT01851759Phase 2Oct 1, 2013People's Liberation Army of China
NCT01831011Phase 2Jul 1, 2008People's Liberation Army of China
Showing 3 of 3 trials
Page 1 / 1

Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
People's Liberation Army of ChinaGovernment2212008
Chinese Academy of Medical SciencesAcademic/Hospital1012016
Peking UniversityAcademic/Hospital1112016
3 organizations
Page 1 / 1