80S Ribosome

PROTEIN NUCLEIC-ACID COMPLEXHomo sapiens

Linked proteins

Drugs acting on this target (52)

Active Pharmaceutical Ingredient	Mechanism Type ▲	Approval Status	API Type	Mechanism of Action
cemiplimab (libtayo)	Antagonist	approved	mAb	PD-1
dorlimomab aritox	Binding agent	experimental	mAb	80S Ribosome binding agent
2B4.11	Inhibitor	experimental	mAb	80S Ribosome inhibitor
609a	Inhibitor	experimental	mAb	80S Ribosome inhibitor
abbv-181	Inhibitor	experimental	mAb	80S Ribosome inhibitor
agen2034	Inhibitor	experimental	mAb	80S Ribosome inhibitor
ak105	Inhibitor	experimental	mAb	80S Ribosome inhibitor
ak111	Inhibitor	experimental	mAb	80S Ribosome inhibitor
amg 404	Inhibitor	experimental	mAb	80S Ribosome inhibitor
apl-501	Inhibitor	experimental	mAb	80S Ribosome inhibitor
bat1306	Inhibitor	experimental	mAb	80S Ribosome inhibitor
bi 754091	Inhibitor	experimental	mAb	80S Ribosome inhibitor
budigalimab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
cc-90006	Inhibitor	experimental	mAb	80S Ribosome inhibitor
cetrelimab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
cs1003	Inhibitor	experimental	mAb	80S Ribosome inhibitor
cx-188	Inhibitor	experimental	mAb	80S Ribosome inhibitor
cycloheximide	Inhibitor	experimental	Small molecule	80S Ribosome inhibitor
dorlimomab aritox	Inhibitor	experimental	mAb	80S Ribosome inhibitor
dostarlimab (Jemperli)	Inhibitor	approved	mAb	80S Ribosome inhibitor
durvalumab (imfinzi)	Inhibitor	approved	mAb	80S Ribosome inhibitor
F520	Inhibitor	experimental	mAb	80S Ribosome inhibitor
genolimzumab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
geptanolimab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
gls-010	Inhibitor	experimental	mAb	80S Ribosome inhibitor
gnr-051	Inhibitor	experimental	mAb	80S Ribosome inhibitor
hlx10	Inhibitor	experimental	mAb	80S Ribosome inhibitor
hx008	Inhibitor	experimental	mAb	80S Ribosome inhibitor
incb106385	Inhibitor	experimental	mAb	80S Ribosome inhibitor
incmga00012	Inhibitor	experimental	mAb	80S Ribosome inhibitor
jtx-4014	Inhibitor	experimental	mAb	80S Ribosome inhibitor
ly3462817	Inhibitor	experimental	mAb	80S Ribosome inhibitor
lzm009	Inhibitor	experimental	mAb	80S Ribosome inhibitor
medi0680	Inhibitor	experimental	mAb	80S Ribosome inhibitor
mt-3724	Inhibitor	experimental	Recombinant protein	80S Ribosome inhibitor
nivolumab (opdivo)	Inhibitor	approved	mAb	80S Ribosome inhibitor
oc-001	Inhibitor	experimental	mAb	80S Ribosome inhibitor
pembrolizumab (keytruda)	Inhibitor	approved	mAb	80S Ribosome inhibitor
sasanlimab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
sct-i10	Inhibitor	experimental	mAb	80S Ribosome inhibitor
sg001	Inhibitor	experimental	mAb	80S Ribosome inhibitor
spartalizumab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
sym021	Inhibitor	experimental	mAb	80S Ribosome inhibitor
taplitumomab paptox	Inhibitor	experimental	mAb	80S Ribosome inhibitor
telimomab aritox	Inhibitor	experimental	mAb	80S Ribosome inhibitor
triprizumab	Inhibitor	experimental	mAb	80S Ribosome inhibitor
ty101	Inhibitor	experimental	mAb	80S Ribosome inhibitor
vb6-845	Inhibitor	experimental	Recombinant protein	80S Ribosome inhibitor
ybl-006	Inhibitor	experimental	mAb	80S Ribosome inhibitor
zolimomab aritox	Inhibitor	experimental	mAb	80S Ribosome inhibitor
ataluren (Translarna)	Modulator	experimental	Small molecule	80S Ribosome modulator
elx-02	Modulator	experimental	Small molecule	80S Ribosome modulator