mebhydrolin napadisilate
Small moleculeexperimental
Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. — Wikipedia
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
1
Earliest trial started Oct 1, 2010 (NCT01584791)
Timeline
No events for the selected filters.
Indications
Approved for
Studied for
Mechanism of action
- Histamine H1 receptorINHIBITOR
HRH1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1- Mol. weight
- 276.38 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMebhydrolin ↗
- ChEMBLCHEMBL1625607 ↗
Also known as
- 1,5-naphthalenedisulfonic acid, compd. with 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)-1h-pyrido(4,3-b)indole (1:2)
- 5-benzyl-1,3,4,5-tetrahydro-2-methyl-2h-pyrido(4,3-b)indole
- diazolin
- diazoline
- diazolinum
- fabahistin
- fabahistin
- fabahistin
- fabahistin
- fabahistin
- incidal
- incidal
- incidal
- mebhydrolin
- mebhydrolin
- mebhydrolin
- mebhydrolin
- mebhydrolin
- mebhydroline
- mebhydroline
- mebhydroline 1,5-naphthalenedisulfonate
- mebhydrolin napadisilate
- mebhydrolin napadisylate
- mebhydrolin napadisylate
- mebhydrolin napadisylate
- mebhydrolin napadisylate
- napadisilate
- napadisilate
- omeril
- omeril
- omeril
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01584791 | Phase 4 | Oct 1, 2010 | Hanmi Pharmaceutical, Seoul National University |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Hanmi Pharmaceutical | For profit | 1 | 0 | 1 | 2010 |
| Seoul National University | Academic/Hospital | 1 | 1 | 1 | 2010 |
2 organizations
Page 1 / 1