sodium phosphate

Small moleculeapproved

Approved

Dec 7, 1953

A sodium phosphate is a generic variety of salts of sodium and phosphate. Phosphate also forms families or condensed anions including di-, tri-, tetra-, and polyphosphates. Most of these salts are known in both anhydrous (water-free) and hydrated forms. The hydrates are more common than the anhydrous forms. — Wikipedia

Clinical trial activity

46 trials · 52 clinical orgs · 43 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Earliest trial started Jun 1, 2001 (NCT00164151)

Timeline

1950s

Dec 7, 1953
Evidence of US Marketing
Dec 7, 1953
Earliest FDA Approval
Dec 7, 1953
Strides Pharma Science — Marketing Organization
Dec 7, 1953
DAVA Pharmaceuticals — Marketing Organization
Aug 10, 1959
Hospira — NDA Secondary Org

1970s

Dec 3, 1975
ICU Medical Inc — First NDA Organization
Dec 3, 1975
ICU Medical Inc — NDA Organization
Sep 5, 1979
Bristol-Myers — Marketing Organization

1980s

Oct 6, 1981
Baxalta — NDA Secondary Org
Oct 6, 1981
Baxter — NDA Secondary Org
Oct 28, 1981
Alcon — NDA Secondary Org
Oct 28, 1981
Nestle — NDA Secondary Org
Apr 2, 1984
B. Braun — NDA Secondary Org
Feb 14, 1985
Bristol-Myers Squibb — Marketing Organization
Apr 3, 1986
ICU Medical Inc — NDA Secondary Org
May 9, 1986
Norbrook — Marketing Organization
Jun 13, 1986
Abraxis — Marketing Organization
Sep 16, 1986
West-Ward Pharmaceutical — Marketing Organization
Dec 16, 1986
Abbott — NDA Secondary Org

1990s

Oct 15, 1990
Barr Laboratories — Marketing Organization
Aug 23, 1991
Pharmacia & Upjohn — Marketing Organization
Nov 27, 1991
Akorn, Inc. — NDA Secondary Org
Nov 27, 1991
Epic Pharma Llc — NDA Secondary Org
May 15, 1992
Mylan — Marketing Organization
Aug 1, 1994
Hikma — Marketing Organization
Sep 27, 1996
Lukare Medical — NDA Secondary Org
Feb 26, 1999
Fresenius — Marketing Organization
Jun 17, 1999
Duramed Research — Marketing Organization

2000s

Sep 21, 2000
Salix — NDA Secondary Org
Jan 1, 2001
Earliest Phase 3 Sponsor(trial)
Apr 30, 2007
Accord Research — Marketing Organization
Mar 31, 2009
Sandoz — Marketing Organization

2010s

Jan 8, 2010
Pharmachemie Bv — Marketing Organization
Jan 1, 2011
Earliest Phase 2 Sponsor(trial)
Dec 30, 2011
Novel Anti-Infective Technologies, LLC — Marketing Organization
Mar 29, 2012
Rising Pharmaceuticals — Marketing Organization
Mar 29, 2012
EXTROVIS — Marketing Organization
Jan 1, 2013
Earliest Phase 1 Sponsor(trial)
May 21, 2015
Sun Pharmaceuticals — Marketing Organization
Jan 13, 2017
Zydus Discovery DMCC — Marketing Organization
Apr 25, 2017
Silvergate Pharmaceuticals — Marketing Organization
Apr 25, 2017
Azurity — Marketing Organization
Dec 22, 2017
Amneal Pharmaceuticals — Marketing Organization
Aug 9, 2018
Sagent Pharmaceuticals, Inc. — Marketing Organization

2020s

Jan 30, 2020
Eugia Pharma — Marketing Organization
Apr 23, 2021
Lotus Pharmaceutical — Marketing Organization
Aug 7, 2023
Daito Pharmaceuticals — Marketing Organization
May 16, 2024
Elite Laboratories, Inc — Marketing Organization
Jun 3, 2024
Alembic — Marketing Organization
Jun 21, 2024
Sankyo — Marketing Organization

Indications

Approved for

Studied for

Mechanism of action

Unspecified targetOTHER
Saline laxative
Indicated for constipation. Also an osmotic agent used to cleanse the bowel prior to colonoscopy.
ElectrolyteSupplementation
Electrolyte supplementation

Combination products

aminosyn ii m in dextrose
with potassium chloride, amino acids, sodium chloride, glucose monohydrate, magnesium
aminosyn w/electrolytes
with potassium chloride, amino acids, sodium chloride, magnesium
Also known as aminosyn ii m, aminosyn ii w/electrolytes
bss plus
with potassium chloride, sodium bicarbonate, sodium chloride, calcium chloride, glucose monohydrate, glutathione, magnesium
Also known as methotrexate sodium
elliotts b solution
with potassium chloride, magnesium sulfate, sodium bicarbonate, sodium chloride, calcium chloride, glucose monohydrate
ionosol b and dextrose
with potassium chloride, lactic acid, sodium chloride, potassium phosphate, glucose monohydrate, magnesium
ionosol mb and dextrose
with potassium chloride, lactic acid, potassium phosphate, glucose monohydrate, magnesium
ionosol t and dextrose
with potassium chloride, potassium lactate, sodium chloride, glucose monohydrate
isolyte s ph
with potassium chloride, sodium acetate, sodium chloride, potassium phosphate, sodium gluconate, magnesium
navstel
with potassium chloride, sodium bicarbonate, sodium chloride, oxiglutatione, calcium chloride, glucose monohydrate, magnesium
phoxillum bk
with potassium chloride, sodium bicarbonate, sodium chloride, calcium chloride, magnesium
Also known as phoxillum b22k
tis-u-sol
with potassium chloride, magnesium sulfate, sodium chloride, potassium phosphate

Approval history

approvedPriority reviewDec 7, 1953
approvedPriority reviewDec 7, 1953

Chemistry & pharmacology

Loading structure…

SMILES

O=P([O-])([O-])O.[Na+].[Na+]

Mol. weight: 141.96 g/mol
Chirality: Achiral Molecule
Inorganic: Yes
Polymer: No
Delivery: Oral, Parenteral
Availability: Prescription Only

Oral

Yes

Parenteral

Yes

Topical

Sources

Also known as

dibasic sodium phosphate
dibasic sodium phosphate
dibasic sodium phosphate, anhydrous
dihydrogen monosodium phosphate
disodium acid phosphate
disodium hydrogen phosphate
disodium hydrogen phosphate anhydrous
disodium phosphate
disodium phosphate
e339
e339
ionosol b
ionosol mb
ionosol t
monobasic sodium phosphate
monobasic sodium phosphate monohydrate
monosodium dihydrogen orthophosphate
monosodium dihydrogen phosphate
monosodium phosphate monohydrate
neutral sodium hydrogen phosphate
neutral sod phos
phosphoric acid, disodium salt
phosphoric acid, disodium salt, 32p-labeled
phosphoric acid, disodium salt, anhydrous
phosphoric acid, disodium salt, dodecahydrate
phosphoric acid, disodium salt, heptahydrate
phosphoric acid monosodium salt
phosphoric acid, monosodium salt
phosphoric acid, monosodium salt, anhydrous
phosphoric acid, monosodium salt, monohydrate
phosphoric acid, sodium (2:3) salt
phosphoric acid, sodium salt
phosphoric acid, trisodium salt
phosphoric acid, trisodium salt , 32p-labeled
phosphoric acid, trisodium salt , dodecahydrate
sodium biphosphate
sodium biphosphate
sodium biphosphate
sodium dihydrogen orthophosphate
sodium dihydrogen phosphate
sodium hydrophosphate
sodium orthophosphate
sodium orthophosphate
sodium phosphate
sodium phosphate
sodium phosphate
sodium phosphate
sodium phosphate
sodium phosphate
sodium phosphate
sodium phosphate, dibasic
sodium phosphate, dibasic
sodium phosphate, dibasic
sodium phosphate, dibasic
sodium phosphate, dibasic anhydrous
sodium phosphate, dibasic anhydrous
sodium phosphate, dibasic anhydrous
sodium phosphate, dibasic (anhydrous)
sodium phosphate, dibasic, anhydrous
sodium phosphate, dibasic, anhydrous
sodium phosphate, dibasic, heptahydrate
sodium phosphate, dibasic, heptahydrate
sodium phosphate, dibasic, heptahydrate
sodium phosphate, dibasic, heptahydrate
sodium phosphate, disodium salt
sodium phosphate monobasic
sodium phosphate monobasic
sodium phosphate, monobasic
sodium phosphate, monobasic
sodium phosphate, monobasic
sodium phosphate, monobasic
sodium phosphate monobasic (anhydrate)
sodium phosphate monobasic (anhydrate)
sodium phosphate monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic anhydrous
sodium phosphate, monobasic, anhydrous
sodium phosphate, monobasic, anhydrous
sodium phosphate, monobasic, anhydrous
sodium phosphate, monobasic, anhydrous
sodium phosphate monobasic monohydrate
sodium phosphate monobasic monohydrate
sodium phosphate, monobasic, monohydrate
sodium phosphate, monobasic, monohydrate
sodium phosphate, monobasic, monohydrate
sodium phosphate, monobasic, monohydrate
sodium phosphates
sodium phosphates
sodium phosphates
sodium phosphate, tribasic
sodium phosphate, tribasic, dodecahydrate
sodium phosphate, unspecified
sodium phosphate, unspecified
soldium phosphate
trisodium phosphate
trisodium phosphate dodecahydrate

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT07233889	N/A	Nov 21, 2025	Huazhong University of Science and Technology
NCT07060222	Phase 4	Jul 20, 2025	University of Guadalajara
NCT06842121	Phase 1	Jan 27, 2025	Baxalta
NCT06652906	Phase 2	Jun 11, 2024	Jiao Tong University
NCT05726097	Phase 3	Feb 1, 2023	Lund University, Region Skane, University of Southern Denmark
NCT05147909	N/A	Apr 1, 2022	The University of Texas, Dallas
NCT05148494	Phase 4	Feb 1, 2022	Government of Canada
NCT05683951	Phase 3	Nov 26, 2021	Daewon Pharmaceutical Co., Ltd.
NCT04071171	Phase 2	Dec 31, 2019	Medical University Innsbruck
NCT04316858	N/A	Mar 1, 2019	Dow University of Health Sciences
NCT03771924	N/A	Feb 28, 2019	German Federal Ministry of Education and Research, Martin Luther University
NCT03817788	Phase 4	Feb 26, 2019	Jilin University
NCT04730245	Phase 1	Jun 1, 2018	Torre Médica Sante, Torre Médica Santé
NCT03234361	N/A	Oct 24, 2017	The University of Texas, Dallas
NCT02961816	Phase 2	Jun 1, 2017	University of Texas at Houston
NCT02539342	Phase 3	Oct 1, 2016	Medical College of Wisconsin
NCT02807337	Phase 2	Aug 1, 2016	University of Tampere, University of Turku
NCT02701673	Phase 1/Phase 2 (Phase 2)	Jun 1, 2016	University of Texas at Houston
NCT02589145	Phase 1/Phase 2 (Phase 2)	Jun 1, 2016	Celgene, University of Texas at Houston
NCT02822131	N/A	Jan 1, 2016	University of Zurich

Showing 20 of 46 trials

Page 1 / 3

Organizations

Research & Development (52)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
University of Texas at Houston	Academic/Hospital	6	6	1	2013
Queen's University, Belfast	Academic/Hospital	3	3	2	2006
Laboratoires Mayoly Spindler	For profit	2	2	2	2011
Norgine	For profit	2	2	1	2002
The University of Texas, Dallas	Academic/Hospital	2	2	1	2017
Bakirkoy Dr. Sadi Konuk Research and Training Hospital	Academic/Hospital	1	1	1	2013
Bausch Health Companies	For profit	1	1	1	2011
Baxalta	For profit	1	1	1	2025
Braintree Laboratories	For profit	1	1	1	2001
Celgene	For profit	1	0	1	2016
Daewon Pharmaceutical Co., Ltd.	For profit	1	1	1	2021
Dow University of Health Sciences	Academic/Hospital	1	1	1	2019
German Federal Ministry of Education and Research	Government	1	0	1	2019
Ghent University	Academic/Hospital	1	1	1	2008
Government of Canada	Government	1	1	1	2022
Government of Korea	Government	1	0	1	2013
Hazleton Eye Specialists	Academic/Hospital	1	0	1	2007
Huazhong University of Science and Technology	Academic/Hospital	1	1	1	2025
Indiana University	Academic/Hospital	1	0	1	2010
Inje University	Academic/Hospital	1	1	1	2010

52 organizations

Page 1 / 3

Marketing (53)

Organization	Org type	Relationship	Date
Abbott	For profit	NDA2	Dec 16, 1986
Abraxis	For profit	MKTG	Jun 13, 1986
Accord Research	For profit	MKTG	Apr 30, 2007
Akorn, Inc.	For profit	NDA2	Nov 27, 1991
Alcon	For profit	NDA2	Oct 28, 1981
Alcon	For profit	SYN	Jul 24, 2008
Alembic	For profit	MKTG	Jun 3, 2024
Amneal Pharmaceuticals	For profit	MKTG	Dec 22, 2017
Azurity	For profit	MKTG	Apr 25, 2017
B. Braun	For profit	NDA2	Apr 2, 1984
Barr Laboratories	For profit	MKTG	Oct 15, 1990
Baxalta	For profit	SYN	Jan 13, 2015
Baxalta	For profit	NDA2	Oct 6, 1981
Baxter	For profit	NDA2	Oct 6, 1981
Bristol-Myers	For profit	MKTG	Sep 5, 1979
Bristol-Myers Squibb	For profit	MKTG	Feb 14, 1985
Bristol-Myers Squibb	For profit	SYN	Apr 14, 1989
DAVA Pharmaceuticals	For profit	MKTG	Dec 7, 1953
Daito Pharmaceuticals	For profit	MKTG	Aug 7, 2023
Duramed Research	For profit	MKTG	Jun 17, 1999
EXTROVIS	For profit	MKTG	Mar 29, 2012
Elite Laboratories, Inc	For profit	MKTG	May 16, 2024
Epic Pharma Llc	For profit	NDA2	Nov 27, 1991
Eugia Pharma	For profit	MKTG	Jan 30, 2020
Eugia Pharma	For profit	SYN	Mar 29, 2012
Fresenius	For profit	MKTG	Feb 26, 1999
Hikma	For profit	MKTG	Aug 1, 1994
Hikma	For profit	SYN	Sep 16, 1986
Hospira	For profit	NDA2	Aug 10, 1959
Hospira	For profit	SYN	Nov 1, 1988
ICU Medical Inc	For profit	NDA2	Apr 3, 1986
ICU Medical Inc	For profit	NDA	Dec 3, 1975
Lotus Pharmaceutical	For profit	MKTG	Apr 23, 2021
Lukare Medical	For profit	NDA2	Sep 27, 1996
Mylan	For profit	MKTG	May 15, 1992
Mylan	For profit	SYN	Mar 29, 2012
Nestle	For profit	NDA2	Oct 28, 1981
Norbrook	For profit	MKTG	May 9, 1986
Novel Anti-Infective Technologies, LLC	For profit	MKTG	Dec 30, 2011
Pharmachemie Bv	For profit	MKTG	Jan 8, 2010
Pharmachemie Bv	For profit	SYN	Jul 8, 1988
Pharmacia & Upjohn	For profit	MKTG	Aug 23, 1991
Rising Pharmaceuticals	For profit	MKTG	Mar 29, 2012
Sagent Pharmaceuticals, Inc.	For profit	MKTG	Aug 9, 2018
Salix	For profit	NDA2	Sep 21, 2000
Sandoz	For profit	MKTG	Mar 31, 2009
Sandoz	For profit	SYN	Mar 31, 2009
Sankyo	For profit	MKTG	Jun 21, 2024
Silvergate Pharmaceuticals	For profit	MKTG	Apr 25, 2017
Strides Pharma Science	For profit	MKTG	Dec 7, 1953
Sun Pharmaceuticals	For profit	MKTG	May 21, 2015
West-Ward Pharmaceutical	For profit	MKTG	Sep 16, 1986
Zydus Discovery DMCC	For profit	MKTG	Jan 13, 2017