Tetanus
A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
Drugs by status
Approved for this indication (4)
Phase 4 trials (15)
- diphtheria, tetanus and whole cell pertussis vaccine
- DTaP, inactivated poliovirus, haemophilus influenzae b conjugate, hepatitis b vaccine
- pneumococcal 13-valent conjugate vaccine
- hepatitis b vaccine (recombinant)
- quinvaxem
- hepatitis a vaccine, inactivated
- attenuated measles vaccine - Edmonston strain
- Tetanus and diphtheria toxoids adsorbed
- Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine
- meningococcal (groups A, C, Y, W) tetanus toxoid conjugate vaccine
- haemophilus influenzae type b conjugate vaccine
- acellular pertussis vaccine (including diptheria and tetanus toxoids)
- diphtheria toxoid
- technetium tc-99m pentetate kit
- Inactivated polio virus - Enhanced
Phase 3 trials (27)
- 23-valent pneumococcal polysaccharide vaccine
- diphtheria, tetanus, and poliovirus vaccine
- diphtheria-tetanus-whole cell pertussis-inactivated poliovirus-haemophilus influenzae b conjugate-hepatitis b vaccine
- menitorix
- meningococcal (groups A, C, Y, W) CRM197 conjugate vaccine
- human papillomavirus quadrivalent (types 6, 11, 16 and 18) vaccine, recombinant
- Measles, Mumps and Rubella Vaccine, Live
- rotavirus vaccine, live, oral, pentavalent
- tritanrix-hepb
- inactivated poliovirus type 2 vaccine
- acellular pertussis vaccine
- glyco-conjugate neisseria meningitidis serogroup c vaccine
- inactivated influenza vaccine
- live attenuated varicella vaccine
- pneumococcal 7-valent conjugate vaccine
- 10-valent Pneumococcal Conjugate Vaccine
- polyribosil-ribitol-phosphate vaccine
- measles, mumps, rubella, varicella vaccine
- measles, mumps, and rubella vaccine
- hib-menac
- bivalent oral polio vaccine (bopv), type 1 and type 3
- polio, inactivated poliovirus vaccine
- human rotavirus, live attenuated
- tnm002
- htig
- Monovalent group C meningococcal vaccine
- Bivalent group A and C meningococcal vaccine
Phase 2 trials (8)
Phase 1 trials (3)
Organizations
Organization Involved with Phase 4 Indications (21)
- Novo Nordisk
- Crucell
- Grifols
- Sanofi
- Sanofi-Aventis
- GlaxoSmithKline
- LG
- Shantha Biotechnics Limited
- Bandim Health Project
- National Institute of Allergy and Infectious Diseases (NIAID)
- Swedish Institute for Infectious Disease Control
- Korea University
- Northwell Health
- Statens Serum Institut
- Tel Aviv University
- Leiden University
- Medical Research Council, The Gambia
- Erasmus University Rotterdam
- University of Liege
- Government of Norway
- Danish Council for Development Research
Organization Involved with Phase 3 Indications (12)
Organization Involved with Phase 2 Indications (4)
Organization Involved with Phase 1 Indications (6)
Organization Involved with Other Experimental Indications (3)