attenuated measles vaccine - Edmonston strain

Trade name: rubeovax

Vaccinewithdrawn

Approved

Mar 1, 1963

Clinical trial activity

25 trials · 40 clinical orgs · 1 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Earliest trial started Nov 2, 1999 (NCT00000815)

Timeline

1960s

Mar 1, 1963
Earliest FDA Approval
Mar 21, 1963
Merck — First NDA Organization
Mar 21, 1963
Merck — NDA Secondary Org
Mar 21, 1963
Merck — NDA Organization

1990s

Jan 1, 1999
Earliest Phase 2 Sponsor(trial)

2000s

Jan 1, 2009
Earliest Phase 1 Sponsor(trial)
Jan 1, 2009
Earliest Phase 3 Sponsor(trial)

Mechanism of action

Measles virusImmunity, active
Measles virus immunity, active

Approval history

withdrawnMar 1, 1963

Chemistry & pharmacology

Chirality: Single Stereoisomer
Inorganic: No
Polymer: No

Oral

Parenteral

Topical

Sources

ChEMBLCHEMBL2109211 ↗

Also known as

attenuated measles vaccine
attenuvax
attenuvax
attenuvax
measles, live attenuated
measles vaccine
measles virus vaccine
measles virus vaccine live
rubeola (measles) vaccine, live attenuated
rubeola (measles) vaccine, live, attenuated
rubeola (measles) vaccine, live further attenuated
rubeovax

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT05794230	Phase 3	Mar 27, 2023	Sanofi-Aventis
NCT04899765	Phase 4	May 20, 2021	Bandim Health Project, Free University of Brussels, University of Southern Denmark, University of Western Australia
NCT04220671	Phase 4	Jan 31, 2020	Bandim Health Project
NCT03296410	Phase 4	Sep 14, 2017	Chinese Academy of Medical Sciences, Government of China
NCT03330171	Phase 4	Apr 10, 2017	University of the Witwatersrand
NCT03170765	N/A	Mar 14, 2017	Postgraduate Institute of Medical Education and Research
NCT03460002	Phase 4	Nov 30, 2016	Bandim Health Project, Statens Serum Institut
NCT02962167	Phase 1	Nov 1, 2016	Mayo Clinic, No More Kids With Cancer, The Matthew Larson Foundation for Pediatric Brain Tumors, University of California, San Francisco, Vyriad, Inc.
NCT02943681	N/A	Oct 1, 2016	Bandim Health Project
NCT02196285	Phase 1	Sep 1, 2015	Bill and Melinda Gates Foundation, Oswaldo Cruz Foundation
NCT02286895	Phase 4	Oct 1, 2014	Centre for Vaccine Development, Mali, PATH, University of Maryland
NCT01668745	Phase 4	May 1, 2013	Bandim Health Project, Centre de Recherche en Sante de Nouna, Burkina Faso, National Institute for Public Health and the Environment, RIVM, Holland, Navrongo Health Research Centre, Ghana, University of Heidelberg
NCT01644721	Phase 4	Jul 1, 2012	Bandim Health Project, Centre de Recherche en Sante de Nouna, Burkina Faso, National Institute for Public Health and the Environment, RIVM, Holland, Navrongo Health Research Centre, Ghana, University of Heidelberg
NCT01557699	Phase 1	Mar 1, 2012	Centers for Disease Control and Prevention (CDC), Dr. D. Y. Patil Dental College & Hospital, Serum Institute of India Pvt. Ltd., University of Colorado, Boulder
NCT01345240	Phase 3	Nov 1, 2011	GlaxoSmithKline
NCT01486355	Phase 4	Aug 1, 2011	Bandim Health Project
NCT02724852	Phase 4	Jul 1, 2011	Chiangmai University
NCT01306006	Phase 4	Feb 1, 2011	Bandim Health Project, Institudo Nacional de Saude Publica INASA
NCT00828022	Phase 1/Phase 2 (Phase 2)	Mar 1, 2009	Ben Gurion University
NCT00829010	Phase 3	Feb 1, 2009	GlaxoSmithKline

Showing 20 of 25 trials

Page 1 / 2

Organizations

Research & Development (40)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
Bandim Health Project	Government	11	11	2	2002
Medical Research Council, The Gambia	Government	4	1	2	2002
Danish Council for Development Research	Government	3	0	1	2002
Novo Nordisk	For profit	3	0	1	2002
Centre de Recherche en Sante de Nouna, Burkina Faso	Academic/Hospital	2	0	1	2012
GlaxoSmithKline	For profit	2	2	1	2009
National Institute for Public Health and the Environment, RIVM, Holland	Government	2	0	1	2012
Navrongo Health Research Centre, Ghana	Academic/Hospital	2	0	1	2012
University of Heidelberg	Academic/Hospital	2	0	1	2012
AP Moeller Foundation	Academic/Hospital	1	0	1	2003
Ben Gurion University	Academic/Hospital	1	1	1	2009
Bill and Melinda Gates Foundation	Academic/Hospital	1	0	1	2015
Centers for Disease Control and Prevention (CDC)	Government	1	0	1	2012
Centre for Vaccine Development, Mali	Academic/Hospital	1	0	1	2014
Chiangmai University	Academic/Hospital	1	1	1	2011
Chinese Academy of Medical Sciences	Academic/Hospital	1	1	1	2017
Dr. D. Y. Patil Dental College & Hospital	Academic/Hospital	1	0	1	2012
Free University of Brussels	Academic/Hospital	1	0	1	2021
Government of China	Government	1	0	1	2017
Institudo Nacional de Saude Publica INASA	Academic/Hospital	1	0	1	2011

40 organizations