live attenuated varicella vaccine

Trade name: Varivax

Vaccineapproved

Approved

Mar 17, 1995

Varicella vaccine, also known as chickenpox vaccine, is a vaccine that protects against chickenpox. One dose of vaccine prevents 95% of moderate disease and 100% of severe disease. Two doses of vaccine are more effective than one. If given to those who are not immune within five days of exposure to chickenpox it prevents most cases of the disease. Vaccinating a large portion of the population also protects those who are not vaccinated. It is given by injection just under the skin. Another vaccine, known as zoster vaccine, is used to prevent diseases caused by the same virus – the varicella zoster virus. — Wikipedia

Clinical trial activity

148 trials · 67 clinical orgs · 1 marketing orgs

Phase 1
19
Phase 2
90
Phase 3
68
Phase 4
34

Earliest trial started Feb 1, 1998 (NCT00005009)

Timeline

1990s

  1. Mar 17, 1995

    Merck — Earliest FDA Approval

  2. Mar 17, 1995

    Merck — NDA Organization

  3. Jan 1, 1998

    Earliest Phase 1 Sponsor(trial)

  4. Jan 1, 1998

    Merck — Earliest Phase 3 Sponsor(trial)

  5. Jan 1, 1999

    Merck — Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Approval history

  • approvedMar 17, 1995

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • gsk209762
  • herpes zoster vaccine
  • live attenuated herpes zoster vaccine
  • live attenuated vaccine against varicella
  • live attenuated varicella vaccine
  • live attenuated varicella virus vaccine
  • live-attenuated varicella-zoster virus vaccine
  • memuru-oka
  • oka-merck
  • okavax
  • varicella virus vaccine live
  • varicella virus vaccine live
  • varicella zoster vaccine
  • varicella-zoster vaccine
  • varicella-zoster virus (live, attenuated)
  • varivax
  • varivax
  • zostavax
  • zostavax
  • zoster vaccine, live

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07054099Phase 3Mar 31, 2026Green Cross Corporation
NCT07293065Phase 3Dec 19, 2025MAXVAX Biotechnology Limited Liability Company
NCT07311148Phase 2Oct 23, 2025Government of China
NCT06961721Phase 4May 31, 2025Changchun BCHT Biotechnology Co., Government of China
NCT06975878Phase 3May 22, 2025Sanofi
NCT06874842Phase 1Mar 13, 2025Government of China
NCT06824181Phase 3Feb 27, 2025Sanofi
NCT06824194Phase 3Feb 18, 2025Sanofi
NCT06851832Phase 1/Phase 2 (Phase 2)Feb 16, 2025Ab&b Biotechnology Co., Ltd., Government of China
NCT06740630Phase 3Dec 17, 2024GlaxoSmithKline
NCT06736041Phase 3Dec 16, 2024Sanofi-Aventis
NCT06654700Phase 3Dec 9, 2024Government of China, MAXVAX Biotechnology Limited Liability Company
NCT06224270Phase 4Oct 31, 2024GlaxoSmithKline, University of Wisconsin
NCT06484686Phase 4Sep 30, 2024Government of China, Sinovac Biotech Co., Ltd
NCT06987942Phase 4Sep 21, 2024Sinovac Biotech Co., Ltd
NCT06447779Phase 3Jul 13, 2024Government of China, MAXVAX Biotechnology Limited Liability Company
NCT06335849Phase 1Mar 27, 2024Government of China, Nucleus Network Ltd
NCT06314724Phase 3Mar 1, 2024Sinovac Biotech Co., Ltd
NCT05839301Phase 3Apr 27, 2023Beijing Tiantan Bio Co., Ltd, China National Biotec Group Co., Ltd, Government of China
NCT05794230Phase 3Mar 27, 2023Sanofi-Aventis
Showing 20 of 148 trials
Page 1 / 8

Organizations

Research & Development (67)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MerckFor profit433651998
Government of ChinaGovernment28742011
GlaxoSmithKlineFor profit181642003
Sinovac Biotech Co., LtdFor profit121232014
National Institute of Allergy and Infectious Diseases (NIAID)Government10551998
Sanofi-AventisFor profit10442005
SanofiFor profit9932009
China National Biotec Group Co., LtdFor profit5432012
SK ChemicalsFor profit5532012
Korea UniversityAcademic/Hospital4032012
University of Colorado, DenverAcademic/Hospital4332010
Changchun Keygen Biological Products Co., Ltd.For profit3312013
Green Cross CorporationFor profit3332015
MAXVAX Biotechnology Limited Liability CompanyFor profit3312024
National Institutes of Health (NIH)Government3011998
Oregon Health and Science UniversityAcademic/Hospital3112013
University of Alabama, BirminghamAcademic/Hospital3212013
University of TorontoAcademic/Hospital3321999
Beijing Tiantan Bio Co., LtdFor profit2012022
Changchun BCHT Biotechnology Co.For profit2222020
67 organizations
Page 1 / 4

Marketing (1)

OrganizationOrg typeRelationshipDate
MerckFor profitNDAMar 17, 1995