Bivalent group A and C meningococcal vaccine
Trade name: Menomune-A/C
Vaccineapproved
Approved
Dec 13, 1976
Clinical trial activity
20 trials · 19 clinical orgs · 1 marketing orgs
Phase 1
2
Phase 2
16
Phase 3
12
Phase 4
3
Earliest trial started Jan 1, 2006 (NCT00136604)
Timeline
1970s
- Dec 13, 1976
Earliest FDA Approval
1990s
- Dec 9, 1999
Sanofi-Aventis — First NDA Organization
- Dec 9, 1999
Sanofi-Aventis — NDA Secondary Org
- Dec 9, 1999
Sanofi-Aventis — NDA Organization
2010s
- Jan 1, 2011
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Studied for
- Dengue · Phase 3
- Dengue Virus · Phase 2
- Dermatitis, Atopic · Phase 2
- Diphtheria · Phase 3
- Diphtheria-Tetanus-Pertussis Vaccine · Phase 3
- Haemophilus influenzae type b · Phase 3
- Hand, Foot and Mouth Disease · Phase 4
- Healthy Volunteers · Phase 3
- Hepatitis B · Phase 3
- Influenza B virus · Phase 3
- Influenza, Human · Phase 3
- Meningitis · Phase 4
- Meningitis, Meningococcal · Phase 3
- Meningococcal Infections · Phase 4
- Pertussis Vaccine · Phase 3
- Poliomyelitis · Phase 3
- Rabies · Phase 3
- Severe Dengue · Phase 3
- Tetanus · Phase 3
- Typhoid Fever · Phase 4
- Vaccines · Phase 3
- Yellow Fever · Phase 3
Mechanism of action
- Neisseria meningitidisImmunity, active
Neisseria meningitidis immunity, active
Approval history
- approvedDec 13, 1976
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- a+c meningococcal polysaccharide vaccine
- group a, c polysaccharide meningococcal vaccine
- mcv-ac vaccine group
- menac
- meningococcal a&c vaccine
- meningococcal a+c vaccine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05397587 | Phase 4 | Jul 30, 2022 | Government of China, Sinovac Biotech Co., Ltd |
| NCT05252715 | Phase 3 | Dec 18, 2021 | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. |
| NCT06314659 | Phase 3 | Sep 17, 2021 | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. |
| NCT04852185 | Phase 4 | Jul 5, 2021 | Fondation Mérieux, International Center for Diarrheal Disease Research, International Vaccine Institute, Kwame Nkrumah University of Science and Technology, University of Cambridge, University of Maryland |
| NCT05386810 | Phase 3 | Nov 5, 2020 | Government of China, Sinovac Biotech Co., Ltd |
| NCT04689191 | Phase 3 | Sep 15, 2020 | Chinese Academy of Medical Sciences, Government of China |
| NCT03562377 | Phase 2 | Jul 13, 2018 | Leo Pharma |
| NCT02919293 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2016 | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd., Government of China, People's Liberation Army of China |
| NCT03714737 | Phase 3 | May 12, 2016 | Government of China |
| NCT06177249 | Phase 3 | Mar 15, 2015 | Government of China, Hualan Biological Bacterin Co. Ltd. |
| NCT02003495 | Phase 3 | Oct 1, 2013 | Beijing Minhai Biotechnology Co., Ltd, Government of China |
| NCT01580033 | Phase 3 | Apr 1, 2012 | Government of China, Royal Biological Co., LTD |
| NCT01428908 | Phase 3 | Sep 1, 2011 | Government of China, Royal Biological Co., LTD |
| NCT01436396 | Phase 3 | Sep 1, 2011 | Sanofi |
| NCT01406509 | Phase 1 | Aug 1, 2011 | Government of China, Royal Biological Co., LTD |
| NCT01430611 | Phase 4 | Aug 1, 2011 | Sanofi, Sanofi-Aventis |
| NCT01187433 | Phase 2 | Aug 1, 2010 | Sanofi |
| NCT00875524 | Phase 2 | Mar 1, 2009 | Sanofi |
| NCT01661751 | Phase 3 | May 1, 2006 | Government of China, Hualan Biological Engineering, Inc. |
| NCT00136604 | Phase 3 | Jan 1, 2006 | GlaxoSmithKline |
Showing 20 of 20 trials
Page 1 / 1
Organizations
Research & Development (19)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Government of China | Government | 11 | 4 | 4 | 2006 |
| Sanofi | For profit | 4 | 4 | 3 | 2009 |
| Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | For profit | 3 | 3 | 2 | 2016 |
| Royal Biological Co., LTD | Academic/Hospital | 3 | 0 | 2 | 2011 |
| Sinovac Biotech Co., Ltd | For profit | 2 | 2 | 2 | 2020 |
| Beijing Minhai Biotechnology Co., Ltd | For profit | 1 | 1 | 1 | 2013 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Fondation Mérieux | Academic/Hospital | 1 | 0 | 1 | 2021 |
| GlaxoSmithKline | For profit | 1 | 1 | 1 | 2006 |
| Hualan Biological Bacterin Co. Ltd. | For profit | 1 | 1 | 1 | 2015 |
| Hualan Biological Engineering, Inc. | For profit | 1 | 1 | 1 | 2006 |
| International Center for Diarrheal Disease Research | Academic/Hospital | 1 | 0 | 1 | 2021 |
| International Vaccine Institute | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Kwame Nkrumah University of Science and Technology | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Leo Pharma | For profit | 1 | 1 | 1 | 2018 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2016 |
| Sanofi-Aventis | For profit | 1 | 0 | 1 | 2011 |
| University of Cambridge | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Maryland | Academic/Hospital | 1 | 0 | 1 | 2021 |
19 organizations
Page 1 / 1
Marketing (2)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Sanofi-Aventis | For profit | NDA2 | Dec 9, 1999 |
| Sanofi-Aventis | For profit | NDA | Dec 9, 1999 |