ubiquinone
Small moleculeexperimental
Coenzyme Q (CoQ ), also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by the human body. The human body mainly produces the form known as coenzyme Q10 (CoQ10, ubidecarenone), but other forms exist. CoQ is used by and found in many organisms, including animals and bacteria. As a result, it can also be obtained from dietary sources, such as meat, fish, seed oils, vegetables, and dietary supplements. — Wikipedia
Clinical trial activity
198 trials · 198 clinical orgs · 0 marketing orgs
Phase 1
29
Phase 2
58
Phase 3
31
Phase 4
23
Earliest trial started Sep 1, 1998 (NCT00004731)
Timeline
Indications
Approved for
Studied for
- Absorption · Phase 1
- Aging · Phase 2
- Alzheimer Disease · Phase 1
- Amyotrophic Lateral Sclerosis · Phase 2
- Apraxias · Phase 3
- Arthritis, Juvenile · Phase 2/Phase 3
- Astrocytoma · Phase 1
- Ataxia · Phase 1
- Atherosclerosis · Phase 4
- Attention Deficit Disorder with Hyperactivity · Phase 3
- Basal Cell Carcinoma · Phase 2
- Bipolar Disorder · Phase 2
- Blood · Phase 1
- Breast Neoplasms · Phase 2
- Burns · Early Phase 1
- Carcinoma, Hepatocellular · Phase 2/Phase 3
- Carcinoma, Squamous Cell · Phase 2
- Cardiomyopathy, Dilated · Phase 4
- Cardiovascular Diseases · Phase 4
- Charcot-Marie-Tooth Disease · Phase 1/Phase 2
- Cognitive Dysfunction · Phase 2/Phase 3
- Colitis, Ulcerative · Phase 2
- Colorectal Neoplasms · Phase 1
- Coronary Artery Disease · Phase 3
- Coronary Stenosis · Phase 3
- COVID-19 · Phase 2
- Crohn Disease · Early Phase 1
- Death, Sudden, Cardiac · Phase 2
- Depression · Phase 2
- Diabetes Mellitus · Phase 4
- Diabetes Mellitus, Type 1 · Phase 2
- Diabetes Mellitus, Type 2 · Phase 2
- Diabetic Retinopathy · Phase 2
- Drug-Related Side Effects and Adverse Reactions · Phase 4
- Drugs, Investigational · Phase 4
- Dry Eye Syndromes · Phase 2
- Dry Socket · Phase 4
- Dyslipidemias · Phase 3
- Fatigue · Phase 1/Phase 2
- Fatigue Syndrome, Chronic · Phase 2/Phase 3
- Fertilization in Vitro · Phase 3
- Frailty · Phase 2
- General Surgery · Phase 2
- Glaucoma, Open-Angle · Phase 4
- Glioblastoma · Phase 1
- Gliosarcoma · Phase 1
- Health · Phase 4
- Health Knowledge, Attitudes, Practice · Phase 4
- Healthy Volunteers · Phase 4
- Heart Arrest · Phase 2
- Heart Failure · Phase 3
- Heart Failure, Diastolic · Phase 4
- Huntington Disease · Phase 3
- Hypercholesterolemia · Phase 4
- Hypersensitivity · Phase 4
- Hypertension · Phase 1
- Hypertension, Pulmonary · Phase 1
- Infertility · Phase 4
- Inflammation · Phase 4
- Jaw Cysts · Phase 2
- Kidney Diseases · Phase 4
- Kidney Failure, Chronic · Phase 4
- Lichen Planus, Oral · Phase 1
- Lower Urinary Tract Symptoms · Phase 2
- Lupus Erythematosus, Systemic · Phase 2
- Menopause · Early Phase 1
- Metabolic Syndrome · Phase 2
- Metabolism · Phase 4
- Mitochondrial Diseases · Phase 3
- Molar, Third · Phase 4
- Multiple Organ Failure · Phase 3
- Multiple Sclerosis · Phase 1/Phase 2
- Muscle Cramp · Phase 2/Phase 3
- Muscle Weakness · Phase 4
- Muscular Dystrophies, Limb-Girdle · Phase 2/Phase 3
- Muscular Dystrophy, Duchenne · Phase 3
- Myalgia · Phase 4
- Myelodysplastic Syndromes · Phase 2/Phase 3
- Myocardium · Early Phase 1
- Neoplasms · Phase 1
- Nervous System Diseases · Phase 2/Phase 3
- Non-alcoholic Fatty Liver Disease · Phase 3
- Osteoporosis · Phase 2
- Ovarian Diseases · Early Phase 1
- Oxidative Stress · Phase 2
- Pain · Phase 2/Phase 3
- Parkinson Disease · Phase 3
- Persian Gulf Syndrome · Phase 3
- Pharmacology · Phase 1
- Postoperative Pain · Phase 4
- Prader-Willi Syndrome · Phase 3
- Pre-Eclampsia · Phase 3
- Pulmonary Disease, Chronic Obstructive · Phase 2
- Quality of Life · Phase 1/Phase 2
- Renal Dialysis · Phase 4
- Renal Insufficiency · Phase 2
- Renal Insufficiency, Chronic · Phase 4
- Respiratory Tract Infections · Phase 1/Phase 2
- Sarcopenia · Phase 2
- Schizophrenia · Phase 2/Phase 3
- Sepsis · Phase 2/Phase 3
- Severe Acute Respiratory Syndrome · Phase 2
- Severe acute respiratory syndrome-related coronavirus · Phase 4
- Skin Care · Early Phase 1
- Sleep Apnea Syndromes · Early Phase 1
- Spinal Cord Injuries · Phase 2
- Supranuclear Palsy, Progressive · Phase 2/Phase 3
- Temporomandibular Joint Disorders · Phase 4
- Urinary Bladder, Overactive · Phase 2
- Vaccines · Phase 4
- Vascular Calcification · Phase 3
- Vestibular Function Tests · Early Phase 1
- Virus Diseases · Phase 4
Mechanism of action
- Unspecified targetOTHER
Supplement
Supplement.
- Unspecified targetAntioxidant
antioxidant
Chemistry & pharmacology
Loading structure…
SMILES
COC1=C(OC)C(=O)C(CCCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)=C(C)C1=O.CS(=O)(=O)[O-]- Mol. weight
- 678.83 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCoenzyme Q10 ↗
- ChEMBLCHEMBL454801 ↗
- ChEMBLCHEMBL4074884 ↗
Also known as
- 2,3-dimethoxy-5-methyl-6-decaprenylbenzoquinone
- api 31510
- api 31510
- armolipid
- armolipid
- bio-quinone q10
- co-enzyme q10
- co-enzyme q10
- co-enzyme q10
- coenzyme q10
- coenzyme q10
- coenzyme q10
- coenzyme q10
- coenzyme q-10
- coenzyme q-10
- coenzyme q10, ion (1-), (all-e)-isomer
- coenzyme q10, (z,z,z,z,z,z,e,e,e)-isomer
- coq10
- coq10
- coq10
- co-q-10
- coq 10
- neuquinon
- neuquinon
- neuquinon
- neuquinon
- q-ter
- ubidecarenone
- ubidecarenone
- ubidecarenone
- ubidecarenone
- ubidecarenone
- ubidecarenone
- ubidecarenone
- ubiquinone
- ubiquinone
- ubiquinone 50
- ubiquinone q10
- ubisemiquinone
- ubisemiquinone radical
- uniquinon
- vitamin q
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07228208 | N/A | Sep 1, 2026 | Medical College of Wisconsin |
| NCT07255079 | N/A | Mar 31, 2026 | 3i Solutions, KGK Science Inc. |
| NCT07260773 | N/A | Dec 31, 2025 | People's Liberation Army of China |
| NCT07307911 | Phase 2 | Nov 10, 2025 | Damanhour University |
| NCT07252518 | N/A | Oct 1, 2025 | Bangladesh Medical University |
| NCT07142096 | N/A | Jul 20, 2025 | Université catholique de Louvain |
| NCT07029360 | N/A | Jul 1, 2025 | University of Pavia |
| NCT06962657 | Phase 2 | Jul 1, 2025 | University of California, San Diego |
| NCT06694727 | Phase 3 | Feb 1, 2025 | Pharma Nord, University of Copenhagen |
| NCT06659406 | N/A | Jan 1, 2025 | College of Physicians and Surgeons Pakistan, University of Faisalabad |
| NCT06743802 | Phase 4 | Dec 20, 2024 | Chongqing Medical University |
| NCT06640465 | Phase 4 | Oct 31, 2024 | Ovation Fertility |
| NCT06361680 | Early Phase 1 (Phase 1) | Oct 30, 2024 | Assiut University |
| NCT06515184 | Phase 3 | Sep 13, 2024 | Department of Defense, University of California, San Diego |
| NCT06555575 | Phase 2 | Sep 1, 2024 | Trio Fertility |
| NCT06619249 | Phase 4 | Aug 23, 2024 | Gdansk University of Physical Education and Sport |
| NCT06570811 | Phase 2 | Aug 1, 2024 | Damanhour University |
| NCT06452134 | Phase 4 | Jul 31, 2024 | Kurdistan University of Medical Sciences |
| NCT06419335 | Early Phase 1 (Phase 1) | Jul 20, 2024 | University of Pennsylvania |
| NCT06620523 | Phase 2 | Jul 18, 2024 | George Washington University |
Showing 20 of 198 trials
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Organizations
Research & Development (198)
198 organizations
Page 1 / 10