← Mechanisms of action

Bacterial DNA gyrase

PROTEIN COMPLEXBacteria

Linked proteins

Drugs acting on this target (24)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
nalidixic acid (neggram)AntagonistapprovedSmall moleculeBacterial DNA gyrase antagonist
norfloxacin (noroxin)AntagonistapprovedSmall moleculeBacterial DNA gyrase antagonist
sparfloxacin (zagam)AntagonistapprovedSmall moleculeBacterial DNA gyrase antagonist
trovafloxacin (trovan)AntagonistapprovedSmall moleculeBacterial DNA gyrase antagonist
AcorafloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
alatrofloxacin (trovan)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
besifloxacin (besivance)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
cinoxacin (cinobac)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
ciprofloxacin (cipro)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
delafloxacin meglumine (baxdela)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
gepotidacinInhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
levonadifloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
lomefloxacin (maxaquin)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
moxifloxacin (avelox)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
nemonoxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
novobiocin (albamycin)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
ofloxacin (floxin)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
pazufloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
pefloxacineInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
prulifloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
sitafloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor
temafloxacin (Omniflox)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
trovafloxacin (trovan)InhibitorapprovedSmall moleculeBacterial DNA gyrase inhibitor
zabofloxacinInhibitorexperimentalSmall moleculeBacterial DNA gyrase inhibitor