← Mechanisms of action
Platelet-derived growth factor receptor
PROTEIN COMPLEXHomo sapiens
Linked proteins
Drugs acting on this target (24)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| becaplermin (regranex) | Agonist | approved | Recombinant protein | Platelet-derived growth factor receptor agonist |
| donafenib (Zepsun) | Antagonist | experimental | Small molecule | Platelet-derived growth factor receptor antagonist |
| abt-869 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| cediranib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| crenolanib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| enmd 2076 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| famitinib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| foretinib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| ilorasertib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| masitinib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| midostaurin (rydapt) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| nintedanib (ofev) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| orantinib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| pazopanib (votrient) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| quizartinib (VANFLYTA) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| regorafenib (stivarga) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| Seralutinib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| su14813 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| sunitinib (sutent) | Inhibitor | approved | Small molecule | Platelet-derived growth factor receptor inhibitor |
| tak-593 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| vatalanib | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| x-82 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| xl820 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |
| xl999 | Inhibitor | experimental | Small molecule | Platelet-derived growth factor receptor inhibitor |