← Mechanisms of action
DNA topoisomerase II
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (21)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| aminocamptothecin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| amonafide | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| amsacrine | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| ava6000 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| banoxantrone | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| becatecarin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| Camsirubicin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| daniquidone | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| dexrazoxane (zinecard) | Inhibitor | approved | Small molecule | DNA topoisomerase II inhibitor |
| etoposide (vepesid) | Inhibitor | approved | Small molecule | DNA topoisomerase II inhibitor |
| intoplicine | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| mk-2248 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| nsc-645809 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| pazufloxacin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| pirarubicin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| rta 744 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| sabarubicin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| sq3370 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| teniposide (vumon) | Inhibitor | approved | Small molecule | DNA topoisomerase II inhibitor |
| vosaroxin | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |
| xk469 | Inhibitor | experimental | Small molecule | DNA topoisomerase II inhibitor |