nsc-645809
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
FLT3 inhibitor
Intercalates to DNA and following metabolic activation, covalently crosslinks DNA strands (PMID: 12007568, PMID:25896848)
- DNA topoisomerase IIINHIBITOR
DNA topoisomerase II inhibitor
Intercalates to DNA and following metabolic activation, covalently crosslinks DNA strands (PMID: 12007568, PMID:25896848)
Chemistry & pharmacology
Loading structure…
SMILES
CCN(CC)CCNc1ccc2ncn3c4ccc(O)cc4c(=O)c1c23- Mol. weight
- 350.42 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL338604 ↗
- ChEMBLCHEMBL3545337 ↗
Also known as
- 5-(2-(diethylamino)ethylamino)--8-hydroxy-6h-imidazo(4,5,1-de)acridin-6-one
- c1311
- c 1311
- c-1311
- c-1311
- c-1311
- nsc-645809
- nsc-645809