← Mechanisms of action
TLR4
SINGLE PROTEINHomo sapiens
Preferred name: Toll-like receptor 4 ChEMBL ↗
Linked proteins
Drugs acting on this target (20)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| as03 | Activator | experimental | Small molecule | TLR4 activator |
| lipopolysaccharide | Activator | experimental | Small molecule | TLR4 activator |
| monophosphoryl lipid a | Activator | experimental | Small molecule | TLR4 activator |
| tara-002 | Activator | experimental | Cell therapy | TLR4 activator |
| cholera toxin | Agonist | experimental | Biological | TLR4 agonist |
| eb05 | Agonist | experimental | Small molecule | TLR4 agonist |
| gla-lsq | Agonist | experimental | Small molecule | TLR4 agonist |
| gsk1795091 | Agonist | experimental | Small molecule | TLR4 agonist |
| ini-2004 | Agonist | experimental | Small molecule | TLR4 agonist |
| om-174 | Agonist | experimental | Small molecule | TLR4 agonist |
| aptoll | Antagonist | experimental | Small molecule | TLR4 antagonist |
| bicyclol | Antagonist | experimental | Small molecule | TLR4 antagonist |
| jkb-121 | Antagonist | experimental | Small molecule | TLR4 antagonist |
| jkb-122 | Antagonist | experimental | Small molecule | TLR4 antagonist |
| 2'-fucosyllactose | Inhibitor | experimental | Small molecule | TLR4 inhibitor |
| avr-48 | Inhibitor | experimental | Small molecule | TLR4 inhibitor |
| ni-0101 | Inhibitor | experimental | mAb | TLR4 inhibitor |
| resatorvid | Inhibitor | experimental | Small molecule | TLR4 inhibitor |
| tak-850 | Inhibitor | experimental | Vaccine | TLR4 inhibitor |
| vb-201 | Inhibitor | experimental | Small molecule | TLR4 inhibitor |