Genetic Diseases, X-Linked
Genetic diseases that are linked to gene mutations on the X CHROMOSOME in humans (X CHROMOSOME, HUMAN) or the X CHROMOSOME in other species. Included here are animal models of human X-linked diseases.
Subtype terms (25)
More specific conditions that are subtypes of Genetic Diseases, X-Linked in the MeSH hierarchy.
- Aicardi Syndrome
5 drugs approved
- Androgen-Insensitivity Syndrome
- Barth Syndrome
2 drugs approved
- Bulbo-Spinal Atrophy, X-Linked
8 drugs (4 approved, 4 experimental)
- Choroideremia
9 drugs (2 approved, 7 experimental)
- Dent Disease
2 drugs approved
- Dyskeratosis Congenita
21 drugs (17 approved, 4 experimental)
- Ectodermal Dysplasia 1, Anhidrotic
2 drugs (1 approved, 1 experimental)
- Fabry Disease
30 drugs (16 approved, 14 experimental)
- Focal Dermal Hypoplasia
- Glycogen Storage Disease Type IIb
1 drug experimental
- Glycogen Storage Disease Type VIII
- Granulomatous Disease, Chronic
52 drugs (30 approved, 22 experimental)
- Hemophilia B
54 drugs (23 approved, 31 experimental)
- Hyper-IgM Immunodeficiency Syndrome, Type 1
9 drugs approved
- Ichthyosis, X-Linked
- Isolated Noncompaction of the Ventricular Myocardium
- Muscular Dystrophy, Duchenne
113 drugs (46 approved, 67 experimental)
- Muscular Dystrophy, Emery-Dreifuss
- Oculocerebrorenal Syndrome
- Ornithine Carbamoyltransferase Deficiency Disease
11 drugs (3 approved, 8 experimental)
- Pelizaeus-Merzbacher Disease
4 drugs (1 approved, 3 experimental)
- Wiskott-Aldrich Syndrome
34 drugs (26 approved, 8 experimental)
- X-Linked Combined Immunodeficiency Diseases
23 drugs (12 approved, 11 experimental)
- X-Linked Intellectual Disability
1 drug approved
Drugs by status
Phase 1 trials (1)
Organizations
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (15)
- DSM
- Spark Therapeutics
- Capricor Inc.
- Retina Foundation of the Southwest
- National Institutes of Health (NIH)
- University of Pittsburgh
- Harvard University
- University of Nebraska
- University of Alberta
- University of Cincinnati
- University of Colorado, Denver
- University of Colorado
- Foundation Fighting Blindness
- National Institute of Child Health and Human Development (NICHD)
- St. Justine's Hospital
Organization Involved with Other Experimental Indications (2)