← All indications
X-Linked Combined Immunodeficiency Diseases
Forms of combined immunodeficiency caused by mutations in the gene for INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT. Both severe and non-severe subtypes of the disease have been identified.
Drugs by status
Phase 3 trials (1)
Phase 2 trials (19)
- plerixafor
- busulfan
- cl20-4i-ef/a-hyc-opt
- mecasermin
- Filgrastim
- palifermin
- magnesium sulfate
- cyclophosphamide
- stem cells
- alemtuzumab
- autologous cd34+ cells
- autologous cd34+ cells transduced withpsrs11.efs.il2rg.pre
- cytarabine
- autologous cd34+ cell transduced with g2scid vector
- threonate
- autologous cd34+ hematopoietic stem cells transduced ex-vivo with a gamma-globin lentiviral vector
- cd34+ hscs transduced with the lentivirus vector, vsv-g pseudotyped cl20-4i-ef1α-hγc-opt
- tyf-il-2rg gene-modified autologous stem cells
- base-edited hematopoietic stem and progenitor cells
Organizations
Organization Involved with Phase 2 Indications (9)
Organization Involved with Phase 1 Indications (2)