Neural Tube Defects
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Subtype terms (7)
More specific conditions that are subtypes of Neural Tube Defects in the MeSH hierarchy.
- Anencephaly
- Arnold-Chiari Malformation
2 drugs approved
- Encephalocele
2 drugs approved
- Meningocele
- Meningomyelocele
4 drugs (2 approved, 2 experimental)
- Pentalogy of Cantrell
- Spinal Dysraphism
7 drugs approved
Drugs by status
Phase 3 trials (5)
Phase 2 trials (5)
Phase 1 trials (1)
Other trials (3)
Organizations
Organization Involved with Phase 3 Indications (2)
Organization Involved with Phase 2 Indications (2)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (5)