CDEK
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cytokine induced killer cells

Cell therapyexperimental

In cell biology, a lymphokine-activated killer cell is a white blood cell, consisting mostly of natural killer, natural killer T, and T cells that has been stimulated to kill tumor cells, but because of the function in which they activate, and the cells they can successfully target, they are classified as different than the classical natural killer and T lymphocyte systems. — Wikipedia

Clinical trial activity

55 trials · 52 clinical orgs · 0 marketing orgs

Phase 1
27
Phase 2
41
Phase 3
7
Phase 4
2

Earliest trial started Jul 1, 1993 (NCT00002535)

Timeline

1990s

  1. Jan 1, 1993

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 1997

    Earliest Phase 1 Sponsor(trial)

2000s

  1. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • cytokine-induced killer cell
  • cytokine induced killer cells
  • cytokine-induced killer cells
  • lymphokine-activated killer cells

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05676190N/AJan 9, 2023People's Liberation Army of China
NCT05955157Phase 2/Phase 3 (Phase 3)Jan 3, 2023University of Malaya
NCT05108077Phase 1/Phase 2 (Phase 2)Jan 1, 2022Belarusian State Medical University, National Academy of Sciences of Belarus
NCT03282435Phase 1Jan 31, 2018Dalian Medical University
NCT03329664Phase 1/Phase 2 (Phase 2)Jan 31, 2018Government of Iran, Sabz Biomedicals, University of Tehran
NCT03124498Phase 1/Phase 2 (Phase 2)Nov 1, 2017Chuan An Biotechnology Co., Ltd.
NCT03146637Phase 2May 1, 2017Benhealth Biopharmaceutical (Shenzhen) Co., Ltd., People's Liberation Army of China
NCT03047525Phase 1/Phase 2 (Phase 2)Feb 20, 2017Harbin Medical University
NCT01631357Phase 2/Phase 3 (Phase 3)Nov 1, 2016Nanjing Medical University, Tianjin Medical University
NCT03002831Phase 2Nov 1, 2016Henan Medical University, Zhengzhou University
NCT03190811Phase 1/Phase 2 (Phase 2)Sep 1, 2016Capital Medical University, Duke University
NCT02886897Phase 1/Phase 2 (Phase 2)Jul 1, 2016Sun Yat-Sen University
NCT02752243Phase 1/Phase 2 (Phase 2)Mar 1, 2016J. W. Goethe University
NCT02489890Phase 2Feb 1, 2016The First People's Hospital of Changzhou
NCT02585908Phase 1/Phase 2 (Phase 2)Nov 1, 2015Beijing Doing Biomedical Co., Ltd.
NCT02621333Phase 2Oct 1, 2015Anyang Regional Hospital, First People's Hospital of Shangqiu, Hebei University, Henan Medical University, Jiaozuo Tumor Hospital, Nanyang Central Hospital, Nanyang Medical College, People's Liberation Army of China, Puyang Oil Field General Hospital, Shanxi Medical University, Shenma Medical Group General Hospital, Tangshan People's Hospital, Xinyang Central Hospital
NCT02490735Phase 2Aug 1, 2015The First People's Hospital of Changzhou
NCT02498756Phase 2Aug 1, 2015The First People's Hospital of Changzhou
NCT02494804Phase 1/Phase 2 (Phase 2)Jul 1, 2015The First People's Hospital of Changzhou
NCT02493582Phase 2Jul 1, 2015The First People's Hospital of Changzhou
Showing 20 of 55 trials
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Organizations

Research & Development (52)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
The First People's Hospital of ChangzhouAcademic/Hospital131332010
People's Liberation Army of ChinaGovernment8622012
Sun Yat-Sen UniversityAcademic/Hospital4422008
Stanford UniversityAcademic/Hospital3322004
University of WisconsinAcademic/Hospital3321993
Henan Medical UniversityAcademic/Hospital2212015
Jinan UniversityAcademic/Hospital2212015
Qingdao UniversityAcademic/Hospital2212011
Anyang Regional HospitalAcademic/Hospital1012015
Azienda Ospedaliera San Gerardo di MonzaAcademic/Hospital1012009
Beijing Doing Biomedical Co., Ltd.For profit1112015
Belarusian State Medical UniversityAcademic/Hospital1012022
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.For profit1112017
Caladrius BiosciencesFor profit1112008
Capital Medical UniversityAcademic/Hospital1112016
China Food and Drug AdministrationGovernment1012012
China Meitan General HospitalAcademic/Hospital1112012
Chuan An Biotechnology Co., Ltd.For profit1112017
Cornell UniversityAcademic/Hospital1111997
Dalian Medical UniversityAcademic/Hospital1112018
52 organizations
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