Tavapadon

Small moleculeexperimental

Clinical trial activity

21 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
13
Phase 2
7
Phase 3
4
Phase 4
0

Earliest trial started Nov 1, 2013 (NCT01981694)

Timeline

2010s

  1. Jan 1, 2013

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1cc(Oc2ncccc2C(F)(F)F)ccc1-c1c(C)c(=O)[nH]c(=O)n1C
Mol. weight
391.35 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • pf06649751
  • pf-06649751

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06895356Phase 1Mar 26, 2025AbbVie
NCT05610189Phase 1Dec 15, 2022Cerevel Therapeutics, LLC
NCT05581823Phase 1Oct 19, 2022Cerevel Therapeutics, LLC
NCT05404542Phase 1May 10, 2022Cerevel Therapeutics, LLC
NCT05404529Phase 1Apr 29, 2022Cerevel Therapeutics, LLC
NCT04760769Phase 3Feb 24, 2021Cerevel Therapeutics, LLC
NCT04542499Phase 3Oct 27, 2020Cerevel Therapeutics, LLC
NCT04241393Phase 1Feb 4, 2020Cerevel Therapeutics, LLC
NCT04295642Phase 1Jan 8, 2020Cerevel Therapeutics, LLC
NCT04223193Phase 3Jan 6, 2020Cerevel Therapeutics, LLC
NCT04201093Phase 3Dec 13, 2019Cerevel Therapeutics, LLC
NCT03185481Phase 2Jun 30, 2017Pfizer
NCT03121664Phase 1Apr 7, 2017Pfizer
NCT02847650Phase 2Oct 17, 2016Pfizer
NCT02687542Phase 2Mar 3, 2016Pfizer
NCT02373072Phase 1Mar 1, 2015Pfizer
NCT02262767Phase 1Nov 1, 2014Pfizer
NCT02224664Phase 1Oct 1, 2014Pfizer
NCT02066909Phase 1Feb 1, 2014Pfizer
NCT01981694Phase 1Nov 1, 2013Pfizer
Showing 20 of 21 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Cerevel Therapeutics, LLCFor profit101022019
PfizerFor profit9922013
AbbVieFor profit2222025
3 organizations
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