CDEK
← Mechanisms of action

DRD3

SINGLE PROTEINHomo sapiens
Preferred name: Dopamine D3 receptor ChEMBL ↗

Linked proteins

Drugs acting on this target (24)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
d390AgonistexperimentalSmall moleculeDRD3 agonist
levodopa (larodopa)AgonistapprovedSmall moleculeDRD3 agonist
PiribedilAgonistexperimentalSmall moleculeDRD3 agonist
sarizotanAgonistexperimentalSmall moleculeDRD3 agonist
sk-09AgonistexperimentalSmall moleculeDRD3 agonist
abt-925AntagonistexperimentalSmall moleculeDRD3 antagonist
ac-201AntagonistexperimentalSmall moleculeDRD3 antagonist
blonanserin (Lonasen)AntagonistexperimentalSmall moleculeDopamine D3 receptor antagonist
chlorprothixene (taractan)AntagonistapprovedSmall moleculeDRD3 antagonist
cvl-936AntagonistexperimentalSmall moleculeDRD3 antagonist
enx-104AntagonistexperimentalSmall moleculeDRD3 antagonist
f17464AntagonistexperimentalSmall moleculeDRD3 antagonist
mesdopetamAntagonistexperimentalSmall moleculeDRD3 antagonist
tiaprizalAntagonistexperimentalSmall moleculeDopamine D3 receptor antagonist
blonanserin (Lonasen)InhibitorexperimentalSmall moleculeDRD3 inhibitor
fallyprideInhibitorexperimentalSmall moleculeDRD3 inhibitor
gsk598809InhibitorexperimentalSmall moleculeDRD3 inhibitor
hec113995paInhibitorexperimentalSmall moleculeDRD3 inhibitor
tak-906InhibitorexperimentalSmall moleculeDRD3 inhibitor
tiaprizalInhibitorexperimentalSmall moleculeDRD3 inhibitor
abbv-932ModulatorexperimentalSmall moleculeDRD3 modulator
cariprazine (vraylar)ModulatorapprovedSmall moleculeDRD3 modulator
bp1.4979Partial agonistexperimentalSmall moleculeDRD3 partial agonist
BrilaroxazinePartial agonistexperimentalSmall moleculeDRD3 partial agonist