lisuride
Trade name: Dopergin
Small moleculeexperimental
Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline family which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth. — Wikipedia
Clinical trial activity
4 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
3
Phase 3
2
Phase 4
0
Earliest trial started Mar 1, 1996 (NCT00000338)
Timeline
Indications
Mechanism of action
HTR2A agonist
HTR1A agonist
- Dopamine receptorAGONIST
Dopamine receptor agonist
Chemistry & pharmacology
Loading structure…
SMILES
CCN(CC)C(=O)N[C@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1- Mol. weight
- 338.46 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLisuride ↗
- ChEMBLCHEMBL157138 ↗
Also known as
- lisurid
- lisurid
- lisurid
- lisurida
- lisurida
- lisuride
- lisuride
- lisuride
- lisuride
- lisuride
- lisuride
- lisuride
- lisuride hydrogen maleate
- lisuride hydrogen maleate
- lisuride hydrogen maleate
- lisuride hydrogen maleate
- lisuride hydrogen maleate
- lisuride hydrogen maleate
- lisuride maleate
- lisuride maleate
- lisuride maleate
- lisuridum
- lisuridum
- lysuride
- lysuride
- lysuride
- mesorgydine
- methylergol carbamide
- methylergol carbamide maleate
- n'-((8alpha)-9,10-didehydro-6-methylergolin-8-yl)-n,n-diethylurea
- n'-((8alpha)-9,10-didehydro-6-methylergolin-8-yl)-n,n-diethylurea
- revanil 200
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00367822 | Phase 3 | Aug 22, 2006 | Axxonis Pharma AG, Somnibene GmbH |
| NCT00408915 | Phase 3 | Jul 1, 2006 | Axxonis Pharma AG |
| NCT00089622 | Phase 2 | Aug 4, 2004 | National Institute of Neurological Disorders and Stroke (NINDS) |
| NCT00000338 | Phase 1 | Mar 1, 1996 | Friends Research Institute, Inc., National Institute on Drug Abuse (NIDA) |
Showing 4 of 4 trials
Page 1 / 1
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Axxonis Pharma AG | For profit | 2 | 2 | 1 | 2006 |
| Friends Research Institute, Inc. | Academic/Hospital | 1 | 0 | 1 | 1996 |
| National Institute of Neurological Disorders and Stroke (NINDS) | Government | 1 | 1 | 1 | 2004 |
| National Institute on Drug Abuse (NIDA) | Government | 1 | 1 | 1 | 1996 |
| Somnibene GmbH | For profit | 1 | 0 | 1 | 2006 |
5 organizations
Page 1 / 1