mescaline
Small moleculeexperimental
Mescaline, also known as mescalin or mezcalin, and in chemical terms 3,4,5-trimethoxyphenethylamine, is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, found in cacti like peyote and San Pedro and known for its serotonergic hallucinogenic effects. — Wikipedia
Clinical trial activity
4 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
0
Phase 3
0
Phase 4
1
Earliest trial started Apr 1, 2014 (NCT02033707)
Timeline
2010s
- Jan 1, 2014
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Serotonin 4 (5-HT4) receptorACTIVATOR
HTR4 activator
- Dopamine receptorACTIVATOR
Dopamine receptor activator
Chemistry & pharmacology
Loading structure…
SMILES
COc1cc(CCN)cc(OC)c1OC- Mol. weight
- 211.26 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMescaline ↗
- ChEMBLCHEMBL26687 ↗
Also known as
- mescaline
- mescaline
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05933213 | Phase 4 | Jul 6, 2023 | Central South University |
| NCT04849013 | Phase 1 | Aug 11, 2021 | University of Basel |
| NCT04227756 | Phase 1 | Apr 1, 2020 | University of Basel |
| NCT02033707 | Phase 1 | Apr 1, 2014 | Johns Hopkins University |
Showing 4 of 4 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Basel | Academic/Hospital | 2 | 2 | 1 | 2020 |
| Central South University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Johns Hopkins University | Academic/Hospital | 1 | 1 | 1 | 2014 |
3 organizations
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