← Mechanisms of action
Histone deacetylase
PROTEIN FAMILYHomo sapiens
Linked proteins
- Histone deacetylase 1 (HDAC1) ↗
- Histone deacetylase 3 (HDAC3) ↗
- Histone deacetylase 6 (HDAC6) ↗
- Histone deacetylase 2 (HDAC2) ↗
- Histone deacetylase 5 (HDAC5) ↗
- Histone deacetylase 7 (HDAC7) ↗
- Histone deacetylase 8 (HDAC8) ↗
- Histone deacetylase 11 (HDAC11) ↗
- Histone deacetylase 4 (HDAC4) ↗
- Histone deacetylase 9 (HDAC9) ↗
- Histone deacetylase 10 (HDAC10) ↗
Drugs acting on this target (15)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| vorinostat (zolinza) | Antagonist | approved | Small molecule | Histone deacetylase antagonist |
| abexinostat | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| belinostat (beleodaq) | Inhibitor | approved | Small molecule | Histone deacetylase inhibitor |
| cudc-101 | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| cudc-907 | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| entinostat | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| givinostat (Duvyzat) | Inhibitor | approved | Small molecule | Histone deacetylase inhibitor |
| panobinostat (farydak) | Inhibitor | approved | Small molecule | Histone deacetylase inhibitor |
| pivanex | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| quisinostat | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| resminostat | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| resveratrol | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| romidepsin (istodax) | Inhibitor | approved | Small molecule | Histone deacetylase inhibitor |
| tacedinaline | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |
| Ursodoxicoltaurine | Inhibitor | experimental | Small molecule | Histone deacetylase inhibitor |